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Table 3 Univariate and multivariate associates of flow mediated dilatation (FMD) in non-dialysis CKD patients

From: The role of plasma triglyceride/high-density lipoprotein cholesterol ratio to predict cardiovascular outcomes in chronic kidney disease

 

FMD

Parameters

Univariate 0 ρ

Multivariate 1 β (P)

ADMA (μmol/l)

−0.58 (<0.001)

NS

Total Cholesterol (mg/dl)

−0.33 (<0.001)

NS

Triglyceride (mg/dl)

−0.19 (0.009)

−0.22 (0.001)

LDL-cholesterol (mg/dl)

−0.14 (0.06)

NS

HDL-cholesterol (mg/dl)

0.37 (<0.001)

0.32 (<0.001)

Triglyceride/HDL-C ratio

−0.34 (<0.001)

−0.25 (0.02)

Total cholesterol/HDL-C ratio

0.30 (<0.001)

NS

NMD (%)

0.45 (<0.001)

0.24 (<0.001)

Diabetes (yes/no)

−0.21 (0.004)

- 0.13 (0.001)

Previous CVD (yes/no)

−0.07 (0.37)

NS

hsCRP (mg/l)

−0.57 (<0.001)

−0.10 (0.03)

Smoking (yes/no)

0.04 (0.45)

NS

SBP (mmHg)

−0.23 (0.001)

−0.10 (0.01)

DBP (mmHg)

−0.20 (0.005)

NS

HOMA-IR

−0.19 (0.008)

NS

Age (yr)

−0.05 (0.45)

NS

Gender (M/F)

0.03 (0.63)

NS

S-albumin (g/dl)

0.26 (<0.001)

0.13 (0.02)

Serum calcium (mg/dl)

0.46 (<0.001)

NS

Serum phosphate (mg/dl)

−0.65 (<0.001)

−0.13 (0.009)

iPTH (pg/ml)

−0.60 (<0.001)

−0.41 (<0.001)

eGFR (ml/min)

0.80 (<0.001)

0.40 (<0.001)

  1. 0Denoted is statistically significant (P < 0.05) ρ values as assessed by Spearman Rank’s test, as well as β estimate and P value from multivariate regression model. The r2 of the multivariate model was 0.76. Variables known to influence FMD levels (age, gender. Diabetes (yes/no), ADMA, Previous CVD, HOMA-IR, calcium, phosphate, SBP, DBP, hsCRP, NMD, albumin, iPTH, eGFR, TG/HDL-C ratio are inserted in the multivariate analyses.