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Table 2 Genotype and allele frequencies of APOC3 gene polymorphisms among ICH cases and healthy controls

From: Effect of apolipoprotein C3 genetic polymorphisms on serum lipid levels and the risk of intracerebral hemorrhage

Genotypes

ICH (%)

Controls (%)

OR (95%CI)

P

1100 CC

58(38.7)

63(42.0)

1.00(Reference)

 

1100 CT

65(43.3)

53(35.3)

1.33(0.80,2.22)

0.27

1100 TT

27(18.0)

34(22.7)

0.86(0.47,1.60)

0.64

1100 C allele frequency

181(60.3)

179(59.7)

1.00(Reference)

 

1100 T allele frequency

119(39.7)

121(40.3)

0.97(0.70,1.35)

0.87

3238 CC

95(63.3)

104(69.3)

1.00(Reference)

 

3238 CG

36(24.0)

39(26.0)

1.01(0.59,1.72)

0.97

3238 GG

19(12.7)

7(4.7)

2.97(1.20,7.38)

0.02

3238 C allele frequency

226(75.3)

247(82.3)

1.00(Reference)

 

3238 G allele frequency

74(24.7)

53(17.7)

1.53(1.03,2.27)

0.04

  1. Adjustment for conventional risk factors, including age, sex, BMI, smoking status, history of hypertension, or diabetes, total cholesterol, HDL-C, LDL-C, and medicine use by which lipid levels are affected
  2. ICH intracerebral hemorrhage