Skip to main content

Table 2 HOMA-IR and HOMA- β of control and experimental rats at baseline and after 28 days of treatment with Tetrapleura tetraptera hydroethanolic extract and metformin

From: Tetrapleura tetraptera spice attenuates high-carbohydrate, high-fat diet-induced obese and type 2 diabetic rats with metabolic syndrome features

Groups Days HOMA-IR HOMA-β
NCD 0 4.18(3.66—5.16)bc 200.98(143.36–346-67)bc
28 4.23(3.71–4.77)bc 192.12(186.6–265.41)bc
T28-T0 −0.10(−0.57–0.83) 22.96(−157.98–63.57)
HCHFD 0 12.31(10.78–14.96)abc 243.13(207.99–299.08)bc
28 14.41(12.59–15.86)abc 274.65(230.55–355.33)Sbc
T28-T0 1.8(0.9–2.9) 28.87(9.44–59.39)
HCHFD200 0 11.58(11–14.86)abc 238.48(222.92–284.91)bc
28 5.31(4.85–6.41)Sbc 240.23(153.31–417.24)bc
T28-T0 −6.36(−9.37_−5.38) −5.57(−82.47–189.53)
DBC 0 28.24(21.39–29.41)a 53.34(44.03–89.46)a
28 26.86(21.11–28.75)a 56.04(44.24–89.15)a
T28-T0 −0.64(−3.01–0.13) 0.86(−0.31–3.52)
DB200 0 27.10(20.58–29.96)a 56.68 (49.59–83.27) a
28 8.74(6.82–10.73)Sabc 110.96(85.22–132.01) Sacb
T28-T0 −17.99(−19.22_−13.76) 49.23 (31.78–68.42)
DB400 0 26.63(21.14–32.28)a 54.44 (49.38–74.84)
28 5.32(4.26–5.44)Sbc 142.75 (97.52–157.70) Sbc
T28-T0 −21.23(−28.01_−15.89) 79.00 (48.14–107.25)
DBMET 0 27.40(23.41–29.12)a 59.08 (49.53–66.67) a
28 6.48(5.4–7.28)Sabc 122.11 (93.53–185.55) Sbc
T28-T0 −21.22(−23.11_16.91) 70.99 (26.86–127.90)
  1. Ssignificant compared with T0 (p < 0.05). asignificant relative to normal control on the same treatment day(p < 0.05). bsignificant compared with HCHFD on the same treatment day. csignificant compared with diabetic control on the same treatment day (p < 0.05). (n = 6)