Table 2 HOMA-IR and HOMA- β of control and experimental rats at baseline and after 28 days of treatment with Tetrapleura tetraptera hydroethanolic extract and metformin

NCD

4.18(3.66—5.16)^bc

200.98(143.36–346-67)^bc

4.23(3.71–4.77)^bc

192.12(186.6–265.41)^bc

−0.10(−0.57–0.83)

22.96(−157.98–63.57)

HCHFD

12.31(10.78–14.96)^abc

243.13(207.99–299.08)^bc

14.41(12.59–15.86)^abc

274.65(230.55–355.33)^Sbc

1.8(0.9–2.9)

28.87(9.44–59.39)

HCHFD200

11.58(11–14.86)^abc

238.48(222.92–284.91)^bc

5.31(4.85–6.41)^Sbc

240.23(153.31–417.24)^bc

−6.36(−9.37_−5.38)

−5.57(−82.47–189.53)

DBC

28.24(21.39–29.41)^a

53.34(44.03–89.46)^a

26.86(21.11–28.75)^a

56.04(44.24–89.15)^a

−0.64(−3.01–0.13)

0.86(−0.31–3.52)

DB200

27.10(20.58–29.96)^a

56.68 (49.59–83.27) ^a

8.74(6.82–10.73)^Sabc

110.96(85.22–132.01) ^Sacb

−17.99(−19.22_−13.76)

49.23 (31.78–68.42)

DB400

26.63(21.14–32.28)^a

54.44 (49.38–74.84)

5.32(4.26–5.44)^Sbc

142.75 (97.52–157.70) ^Sbc

−21.23(−28.01_−15.89)

79.00 (48.14–107.25)

DBMET

27.40(23.41–29.12)^a

59.08 (49.53–66.67) ^a

6.48(5.4–7.28)^Sabc

122.11 (93.53–185.55) ^Sbc

−21.22(−23.11_16.91)

70.99 (26.86–127.90)