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Table 6 Plasma oxidative stress and antioxidant enzymes in treated and untreated high-carbohydrate high-fat fed and type 2 diabetic rats

From: Tetrapleura tetraptera spice attenuates high-carbohydrate, high-fat diet-induced obese and type 2 diabetic rats with metabolic syndrome features

Groups TBARS (nmol/mg protein) GSH (μmol/L) Plasma uric acid (μmol/L) SOD(Unit/mg protein) HbA1C(g/kg Hb) AGE (mg/mL)
NCD 5.33(4.98–6.20)bc 34(32–36)bc 31.8(28.9–34.1)bc 142(136–146)bc 55.5(50.8–60.1)bc 3.32(2.9–3.5)c
HCHFD 9.63(8.79–10.21)a 21(19–23)a 45.35(44.2–45.9)c 87(82–95) ac 92.25(89.6–96.7)c 3.45(3.1–3.8)c
HCHFD200 6.92(6.52–8.20)c 27.5(25–29)abc 41.95(41.2–42.5)abc 137(129–144)bc 70.6(67.8–72.6)abc 3.4(2.9–3.7)c
DBC 10.44(9.57–11.20)a 22(19–24)a 56.65(54.8–58.3) ab 74.5(72–80)b 103.8(99.3–108.3) ab 5.05(4.6–5.3)
DB200 7.97(6.89–8.26)abc 29.5(27–32)bc 45.95(44.6–47.9) ac 131.5(130–134)bc 78.55(76.3–81.5)abc 4.8(4.2–5.1)
DB400 5.94(4.6–7.39)bc 33.5(32–36)bc 33.75(32–35.4)bc 135(128–137)bc 51.45(49.3–55.2)bc 3.17(2.9–3.6)c
DBMET 6.22(4.8–7.36)bc 31.5(29–36)bc 36.3(35.8–37.3)abc 126(122–132)abc 61.05(57.6–62.3)bc 3.75(3.4–4.2)c
  1. asignificant relative to normal control (p < 0.05). bsignificant compared with HCHFD (p < 0.05). csignificant compared with diabetic control (p < 0.05). (n = 6)