Parameter | 8 weeks | 12 weeks | ||||
---|---|---|---|---|---|---|
Control | HFD ED | HFD CO | Control | HFD ED | HFD CO | |
n | 9 | 12 | 12 | 10 | 9 | 10 |
Liver (% Bw) | 4.4 ± 0.5 | 4.5 ± 0.3 | 4.2 ± 0.2 | 4.6 ± 0.1ab | 4.3 ± 0.1a | 4.8 ± 0.1b |
Hepatic total lipid (mg/g dry liver weight)a | 4.6 ± 0.3a | 3.9 ± 0.2a | 6.9 ± 0.4b | 5.2 ± 0.5ab | 4.7 ± 0.3a | 6.5 ± 0.5b |
Plasma triglycerides (mmole/L) | 0.9 ± 0.1ab | 1.1 ± 0.1a | 0.7 ± 0.0b | 1.2 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.1 |
Hepatic total cholesterol (mg/g dry liver weight) | 5.0 ± 0.2a | 6.2 ± 0.4b | 6.0 ± 0.1b | 4.4 ± 0.1a | 6.4 ± 0.2b | 6.4 ± 0.2b |
Plasma total cholesterol (mmole/L) | 5.6 ± 0.9 | 5.5 ± 0.8 | 5.4 ± 0.9 | 6.3 ± 0.3a | 6.0 ± 0.3a | 9.2 ± 0.5b |