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Table 2 Dietary effects on liver weight, plasma and hepatic lipid content

From: Eicosapentaenoic and docosahexaenoic acid-enriched high fat diet delays the development of fatty liver in mice

Parameter 8 weeks 12 weeks
Control HFD ED HFD CO Control HFD ED HFD CO
n 9 12 12 10 9 10
Liver (% Bw) 4.4 ± 0.5 4.5 ± 0.3 4.2 ± 0.2 4.6 ± 0.1ab 4.3 ± 0.1a 4.8 ± 0.1b
Hepatic total lipid (mg/g dry liver weight)a 4.6 ± 0.3a 3.9 ± 0.2a 6.9 ± 0.4b 5.2 ± 0.5ab 4.7 ± 0.3a 6.5 ± 0.5b
Plasma triglycerides (mmole/L) 0.9 ± 0.1ab 1.1 ± 0.1a 0.7 ± 0.0b 1.2 ± 0.1 1.0 ± 0.1 1.0 ± 0.1
Hepatic total cholesterol (mg/g dry liver weight) 5.0 ± 0.2a 6.2 ± 0.4b 6.0 ± 0.1b 4.4 ± 0.1a 6.4 ± 0.2b 6.4 ± 0.2b
Plasma total cholesterol (mmole/L) 5.6 ± 0.9 5.5 ± 0.8 5.4 ± 0.9 6.3 ± 0.3a 6.0 ± 0.3a 9.2 ± 0.5b
  1. Data are shown as mean ± SEM; different letters show significant differences tested by ANOVA followed by Tukey’s multiple comparison test
  2. aLipid measurements n = 7, 8, 8 for Control, HFD-EPA/DHA and HFD-corn oil, respectively. High fat diet (HFD)- EPA/DHA (ED) and HFD-corn oil (CO)