Table 3 Liver fatty acids profiles

Neutral Lipids

Control

HFD ED

HFD CO

Control

HFD ED

HFD CO

Sum SFA

15.5 ± 1.3

12.3 ± 2.0

26.3 ± 1.7

20.6 ± 2.5

15.6 ± 1.8

23.6 ± 1.3

C16:0

13.5 ± 1.2^a

10.2 ± 1.5^a

23.9 ± 1.6^b

18.2 ± 2.3^ab

13.8 ± 1.6^a

21.2 ± 1.2^b

C18:0

2.1 ± 0.1

2.1 ± 0.5

2.4 ± 0.2

2.3 ± 0.2^ab

1.9 ± 0.2^a

2.4 ± 0.1^b

Sum MUFA

28.0 ± 3.3

11.0 ± 2.8

44.3 ± 3.5

37.1 ± 6.3

19.9 ± 3.5

49.6 ± 4.0

C16:1n-7

4.1 ± 0.5^a

2.2 ± 0.6^b

1.8 ± 0.2^b

5.5 ± 0.9^a

4.2 ± 0.7^a

9.6 ± 0.7^b

C18:1n-9

19.4 ± 2.1^a

7.9 ± 1.9^b

33.9 ± 2.6^c

25.1 ± 4.4^ab

13.9 ± 2.4^a

31.7 ± 2.6^b

C18:1n-7

4.5 ± 0.7^a

0.9 ± 0.3^b

8.5 ± 0.8^c

6.5 ± 1.1^a

1.7 ± 0.4^b

8.2 ± 0.7^a

Sum n-6 PUFA

9.4 ± 0.4

7.7 ± 1.3

14.9 ± 0.8

8.9 ± 1.0

7.9 ± 0.5

17.1 ± 0.9

C18:2n-6

6.9 ± 0.3^a

6.8 ± 1.0^a

14.9 ± 0.8^b

7.2 ± 0.7^a

7.9 ± 0.5^a

14.9 ± 0.7^b

C20:4n-6

2.4 ± 0.1^a

0.9 ± 0.3^b

0.0 ± 0.0^c

1.7 ± 0.2^a

0.0 ± 0.0^b

2.2 ± 0.3^a

Sum n-3 PUFA

0.0 ± 0.0

9.2 ± 1.5

0.0 ± 0.0

0.3 ± 0.0

11.5 ± 1.3

0.0 ± 0.0

C20:5n-3 (EPA)

0.0 ± 0.0^a

1.6 ± 0.3^b

0.0 ± 0.0^a

0.0 ± 0.0^a

2.3 ± 0.3^b

0.0 ± 0.0^a

C22:6n-3 (DHA)

0.0 ± 0.0^a

7.6 ± 1.2^b

0.0 ± 0.0^a

0.3 ± 0.0^a

9.3 ± 1.0^b

0.0 ± 0.0^a

Phospholipids

Sum SFA

19.4 ± 0.7

23.0 ± 1.2

17.1 ± 0.5

20.5 ± 0.5

21.7 ± 1.2

17.8 ± 1.0

C16:0

11.6 ± 0.4^a

15.3 ± 0.7^b

10.7 ± 0.3^a

12.6 ± 0.3^ab

14.7 ± 0.8^b

11.2 ± 0.6^a

C18:0

7.8 ± 0.3^a

7.7 ± 0.5^a

6.4 ± 0.2^b

8.0 ± 0.2^a

7.0 ± 0.4^ab

6.6 ± 0.4^b

Sum MUFA

7.2 ± 0.2

6.5 ± 0.4

6.40.2

7.5 ± 0.1

6.2 ± 0.3

6.3 ± 0.2

C16:1n-7

1.0 ± 0.0

0.9 ± 0.1

1.1 ± 0.1

0.9 ± 0.0

0.9 ± 0.1

1.0 ± 0.0

C18:1n-9

6.2 ± 0.2^a

5.6 ± 0.3^ab

5.3 ± 0.1^b

6.6 ± 0.1^a

5.4 ± 0.2^b

5.3 ± 0.2^b

Sum n-6 PUFA

21.2 ± 0.8

11.7 ± 1.1

19.8 ± 1.4

19.6 ± 0.8

11.7 ± 0.8

20.8 ± 0.9

C18:2n-6

6.0 ± 0.3

6.6 ± 1.0

6.2 ± 0.9

5.4 ± 0.2a

6.6 ± 0.5ab

7.7 ± 0.4b

C20:3n-6

1.2 ± 0.1^a

0.4 ± 0.0^b

2.0 ± 0.1^c

1.2 ± 0.1^a

0.6 ± 0.0^b

1.7 ± 0.1^c

C20:4n-6

13.9 ± 0.4^a

4.7 ± 0.1^b

11.6 ± 0.4^c

13.0 ± 0.5^a

4.6 ± 0.3^b

11.3 ± 0.4^c

Sum n-3 PUFA

3.5 ± 0.1

13.2 ± 2.0

2.8 ± 0.1

2.7 ± 0.2

12.4 ± 0.8

2.2 ± 0.1

C20:5n-3 (EPA)

0.0 ± 0.0^a

0.4 ± 0.0^b

0.0 ± 0.0^a

0.0 ± 0.0^a

0.4 ± 0.0^b

0.0 ± 0.0^a

C22:6n-3 (DHA)

3.5 ± 0.1^a

12.7 ± 2.0^b

2.8 ± 0.1^a

2.7 ± 0.2^a

12.4 ± 0.8^b

2.2 ± 0.1^a