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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Palmitate induces cisternal ER expansion via the activation of XBP-1/CCTα-mediated phospholipid accumulation in RAW 264.7 cells

Fig. 1

Palmitate induces necrosis in RAW 264.7 cells. Cells were treated with palmitate at the indicated concentration or 4 μM staurosporine for 24 h. Changes in ER structure were examined by transmission electron microscopy (a). The treated cells were stained with the APOPercentage dye (APOPercentage™ kit, Biocolor, Belfast, NIreland) for 1 h (b) and, by annexin V-FITC/propidium iodide (PI) and were analyzed by flow cytometry (c)

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