Fig. 8From: Palmitate induces cisternal ER expansion via the activation of XBP-1/CCTα-mediated phospholipid accumulation in RAW 264.7 cellsPalmitate-induced cisternal ER expansion is attenuated by the down-regulation of XBP-1 or CCTα in RAW 264.7 cells. Cells were transfected with control, XBP-1 or CCTα siRNAs. After 48 h transfection, the transfected cells were treated with 400 μM palmitate for 24 h. Changes in ER structure were examined by transmission electron microscopyBack to article page