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Table 2 Blood and Lipid Profiles by HDL Group

From: Lipoprotein heterogeneity in persons with Spinal Cord Injury: a model of prolonged sitting and restricted physical activity

 

AB-Normal

AB-Low

SCI-Normal

SCI- Low

p-value

Post-Hoc

Glucose (mmol/l)

4.9 (4.7, 5.1)

5.0 (4.6,5.5)

4.4 (4.1, 4.6)

4.3 (4.0, 4.6)

<0.0001

1,2

Insulin (mU/ml)

18.1 (13.2, 22.9)

27.5 (17.8, 37.1)

19.1 (14.3, 23.8)

27.6 (22.0, 33.2)

0.03

 

Lipids

      

Triglycerides (mg/dl)

91 (75, 107)

124 (94, 153)

109 (93, 125)

137 (118, 157)

<0.001

2

Total Cholesterol (mg/dl)

187 (176, 197)

178 (158, 196)

181 (170, 192)

166 (153, 179)

0.1

 

LDL-C (mg/dl)

109 (100, 118)

117 (101, 133)

110 (101, 119)

104 (93, 114)

NS

 

HDL-C (mg/dl)

59 (56, 62)

37 (31, 42)

49 (46, 52)

35 (31, 38)

<0.0001

1,2,3,4

NMR lipoprotein particle measures

     

VLDL Particle Number (μmol/l)

53.4 (45.3, 61.7)

61.5 (46.3, 76.8)

56.4 (48.3, 64.6)

71.8 (62.1, 81.6)

<0.05

2

     Large VLDL (μmol/l)

2.6 (1.4, 3.8)

4.3 (2.6, 7.1)

3.6 (2.4, 4.8)

5.5 (4.0, 6.9)

<0.05

2

     Small VLDL (μmol/l)

31.8 (26.7, 37.0)

30.2 (16.6, 35.7)

32.9 (27.9, 38.1)

41.2 (35.0, 49.3)

<0.05

5

LDL Particle Number (nmol/l)

1088 (989, 1187)

1349 (1166, 1534)

1211 (1112, 1309)

1175 (1056, 1293)

0.08

 

     IDL (nmol/l)

89 (67, 112)

97 (55, 139)

111 (90, 132)

87 (62, 112)

NS

 

     Large LDL (nmol/l)

503 (444, 561)

372 (265, 478)

467 (409, 524)

390 (321, 459)

0.06

 

     Small LDL (nmol/l)

504 (421, 587)

887 (735, 1041)

633 (551, 715)

698 (599, 796)

<0.0001

2,3

HDL Particle Number (μmol/l)

35.6 (34.2, 37.0)

28.2 (25.6, 30.8)

31.1 (29.7, 32.5)

25.2 (23.5, 27.0)

<0.0001

1,2,3,6

     Large HDL (μmol/l)

6.6 (5.9, 7.3)

2.1 (0.7, 3.4)

4.6 (3.9, 5.3)

2.4 (1.5, 3.3)

<0.0001

1,2,3,4,6

     Small HDL (μmol/l)

16.7 (15.3, 18.1)

17.9 (15.2, 20.5)

15.8 (14.4, 17.2)

14.6 (12.9, 16.3)

NS

 

VLDL Particle Size (nm)

45.7 (43.8, 47.7)

49.0 (45.4, 52.6)

47.8 (45.9, 49.7)

48.5 (46.2, 50.8)

NS

 

LDL Particle Size (nm)

20.9 (20.8, 21.1)

20.3 (20.0, 20.5)

20.9 (20.8, 21.1)

20.6 (20.4, 20.8)

<0.0001

2,3,4,6

HDL Particle Size (nm)

9.2 (9.1, 9.3)

8.6 (8.4, 8.8)

9.0 (8.9, 9.2)

8.7 (8.6, 8.9)

<0.0001

2,3,4,6

  1. Data are expressed as group mean (95 % CI). AB able-bodied, SCI spinal cord injury, Normal: HDL-C >40 mg/dl; Low: HDL-C ≤40 mg/dl; NMR nuclear magnetic resonance, VLDL very low density lipoprotein, LDL low density lipoprotein, IDL intermediate density lipoprotein, HDL high density lipoprotein. P-values represent significant group main effects. 1AB-Normal v. SCI-Normal = p < 0.05; 2AB-Normal v. SCI-Low = p < 0.05; 3AB-Normal v. AB-Low = p < 0.05; 4SCI-Normal v. AB-Low = p < 0.05; 5AB-Normal v. SCI-Low = p = 0.06; 6SCI-Normal v. SCI-Low = p < 0.05