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Table 3 Lipid metabolites that showed more than 10-fold and significant differences between humans and rats

From: Comparison of circulating lipid profiles between fasting humans and three animal species used in preclinical studies: mice, rats and rabbits

>10-fold

<10-fold

Metabolite

Fold

Metabolite

Fold

21:4 ChE

17.6192

34:3 PCb

0.0648

21:5 ChEa

12.2477

36:3 PCb

0.0827

22:4 ChE

20.3018

38:4 PCa

0.0844

23:6 ChE

13.9319

34:2 ePCa

0.0717

24:6 ChE

18.5058

34:2 ePCb

0.0713

  

36:2 ePC

0.0724

  

36:3 ePCa

0.0934

  

36:3 ePCb

0.0516

  

36:5 ePC

0.0729

  

38:4 ePC

0.0782

  

38:5 ePCb

0.0600

  

40:4 ePC

0.0877

  

42:5 ePC

0.0947

  

44:5 ePC

0.0411

  

36:1 PE

0.0997

  

34:3 ePE

0.0656

  

36:2 ePEb

0.0409

  

36:3 ePE

0.0331

  

38:5 ePE

0.0778

  

32:1 SM

0.0293

  

38:1 SM

0.0626

  

39:1 SM

0.0339

  

40:2 SMa

0.0957

  

43:2 SM

0.0401

  

34:1 di-HexCer

0.0186

  

42:2 di-HexCer

0.0643

  

34:1 DGa

0.0648

  

34:2 DGa

0.0523

  

36:2 DG

0.0945

  

14:1 ChE

0.0513

  

18:4 ChE

0.0565

  

CoQ10

0.0174

  1. If more than two lipid species possessed the same chemical formula, alphabetical letters were put after each lipid molecule class to distinguish them from each other (Additional file 1: Table S1)
  2. ChE cholesteryl ester, PC phosphatidylcholine, ePC ether-type phosphatidylcholine, PE phosphatidylethanolamine, ePE ether-type phosphatidylethanolamine, SM sphingomyelin, HexCer hexosylceramide, DG diacylglycerol, CoQ coenzyme Q