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Table 4 The total and stratified analysis of the ABCB1 C3435T polymorphism on myopathy due to statin treatment

From: ABCB1 C3435T polymorphism and the lipid-lowering response in hypercholesterolemic patients on statins: a meta-analysis

Myalgia

Genotype

OR (95 % CI)

Pa

P

The total group

CC vs. CT+TT

0.69(0.19,2.53)

0.09

0.57

 

CC+CT vs. TT

0.75(0.06,9.93)

0.01

0.82

 

CC vs. TT

0.75(0.06,9.93)

0.01

0.82

 

C vs. T

0.77(0.22,2.62)

0.002

0.67

The subgroup of more than 5 months

CC vs. CT+TT

0.33(0.11,0.98)

0.89

0.05

 

CC+CT vs. TT

0.30(0.12,0.75)

0.93

0.01

 

CC vs. TT

0.20(0.06,0.70)

0.55

0.01

 

C vs. T

0.42(0.23,0.75)

0.94

0.004

  1. a p value of Q-test for heterogeneity test