Fig. 3From: High dietary cholesterol and ovariectomy in rats repress gene expression of key markers of VLDL and bile acid metabolism in liverHepatic mRNA expression of genes related to bile acid metabolism in sham (■) and ovariectomized (Ovx, gray square symbol) rats fed a standard diet (SD), a SD + 0.25 % cholesterol diet (SD + Chol), and a high fat + 0.25 % cholesterol diet (HF + Chol). Values are mean ± SE with n = 8 rats per group. ***Significantly different from respective Sham rats (P < 0.001); †Significantly different from rats fed the respective SD diet (P < 0.05), ††(P < 0.01), †††(P < 0.001); δδSignificantly different from rats fed the respective SD + Chol diet (P < 0.01), δδδ(P < 0.001). Abcg5/Abcg8, ATP-cassette binding protein G5 and G8; Mdr2, multidrug resistance-associated transporter 2; Bsep, bile salt export pump; Ntcp, Na + −taurocholate cotransporting polypeptide; Cyp7a1, cytochrome P450 7A1; Fxr, farnesoid X receptorBack to article page