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Fig. 3 | Lipids in Health and Disease

Fig. 3

From: High dietary cholesterol and ovariectomy in rats repress gene expression of key markers of VLDL and bile acid metabolism in liver

Fig. 3

Hepatic mRNA expression of genes related to bile acid metabolism in sham (■) and ovariectomized (Ovx, gray square symbol) rats fed a standard diet (SD), a SD + 0.25 % cholesterol diet (SD + Chol), and a high fat + 0.25 % cholesterol diet (HF + Chol). Values are mean ± SE with n = 8 rats per group. ***Significantly different from respective Sham rats (P < 0.001); Significantly different from rats fed the respective SD diet (P < 0.05), ††(P < 0.01), †††(P < 0.001); δδSignificantly different from rats fed the respective SD + Chol diet (P < 0.01), δδδ(P < 0.001). Abcg5/Abcg8, ATP-cassette binding protein G5 and G8; Mdr2, multidrug resistance-associated transporter 2; Bsep, bile salt export pump; Ntcp, Na + −taurocholate cotransporting polypeptide; Cyp7a1, cytochrome P450 7A1; Fxr, farnesoid X receptor

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