The association of cardiovascular risk factors with saturated fatty acids and fatty acid desaturase indices in erythrocyte in middle-aged Korean adults

Kim, Seung Rye; Jeon, So Yeon; Lee, Seung-Min

doi:10.1186/s12944-015-0135-x

Lipids in Health and Disease

Table 2 Correlation analysis between erythrocyte membrane phospholipid fatty acids and cardiovascular risk factors

From: The association of cardiovascular risk factors with saturated fatty acids and fatty acid desaturase indices in erythrocyte in middle-aged Korean adults

	BMI	Waist circumference	TG	Apo B	TC	LDL-C	HDL-C	SBP	DBP	FBS	Insulin	AI	HbA1c	HOMA-IR	homocysteine	hs-CRP
C14:0 Myristic acid	0.283^*	0.285^*	0.480^**	0.130	−0.053	−0.100	−0.322^*	0.150	0.177	0.308^*	0.429^**	0.343^**	0.173	0.457^**	0.145	0.088
C16:0 Palmitic acid	0.256	0.279^*	0.375^**	−0.007	−0.198	−0.299^*	−0.297^*	0.480^**	0.496^**	0.146	0.129	0.122	0.000	0.209	0.033	0.139
C18:0 Stearic acid	0.043	0.059	−0.341^**	−0.189	−0.058	0.032	0.100	−0.326^*	−0.329^*	−0.150	−0.011	−0.205	−0.004	−0.064	−0.122	−0.038
C24:0 Lignoceric acid	−0.041	0.134	−0.058	−0.075	−0.015	0.061	0.044	−0.176	−0.221	0.163	−0.085	−0.053	0.043	−0.037	0.138	−0.311^*
C16:1n7, Palmitoleic acid	0.059	−0.022	0.454^**	0.114	0.091	−0.079	0.023	0.140	0.209	0.228	0.098	0.078	−0.008	0.123	0.088	0.122
C18:1n9, Oleic acid	0.099	0.213	0.523^**	0.345^**	0.021	−0.068	−0.157	.0387^**	0.407^**	0.033	0.269^*	0.212	0.034	0.274^*	0.269^*	0.110
C20:1n9, Eicosenoic acid	0.093	0.043	−0.328^*	−0.107	−0.156	0.022	−0.127	−0.288^*	−0.249	0.072	0.054	0.012	0.171	0.076	−0.184	0.115
C24:1n9, Nervonic acid	−0.057	0.003	−0.227	−0.077	0.048	0.160	0.106	−0.316^*	−0.338^*	0.098	−0.056	−0.020	0.105	−0.039	0.115	−0.201
C18:2n6 (LA)	−0.214	−0.335^*	−0.179	0.066	0.364^**	0.376^**	0.216	−0.052	−0.069	−0.245	−0.109	0.013	−0.123	−0.195	−0.145	0.037
C18:3n6 (GLA)	0.125	0.090	0.359^**	0.085	0.049	0.033	−0.219	0.018	0.044	0.324^*	0.349^**	0.265^*	0.250	0.286^*	0.029	0.041
C20:2n6 (EDA)	−0.136	−0.140	−0.092	0.051	0.104	0.005	0.283^*	−0.096	−0.087	−0.113	−0.056	−0.248	0.055	−0.038	0.079	−0.042
C20:3n6 (DGLA)	0.168	0.080	0.065	0.127	0.095	0.149	−0.160	0.212	0.241	0.046	0.163	0.181	0.209	0.137	0.127	0.245
C20:4n6 (AA)	−0.080	−0.020	−0.469^**	−0.284^*	−0.159	0.012	0.004	−0.284^*	−0.276^*	−0.034	−0.188	−0.201	0.108	−0.220	−0.051	0.005
C22:4n6 (DTA)	0.165	0.147	−0.244	−0.147	−0.084	0.065	−0.140	−0.027	−0.011	0.145	0.165	−0.037	0.131	0.130	0.003	0.064
C22:5n6 (DPA)	−0.178	−0.104	0.128	0.199	0.287^*	0.245	0.166	−0.032	−0.090	−0.174	−0.165	−0.001	−0.265^*	−0.224	0.048	−0.006
C18:3n3 (ALNA)	0.024	−0.057	0.215	0.011	−0.029	−0.081	−0.048	0.085	0.050	0.043	0.087	0.060	−0.168	−0.012	−0.162	0.123
C20:5n3 (EPA)	0.181	0.202	−0.166	−0.113	−0.221	−0.237	−0.041	0.017	0.032	0.138	−0.035	−0.053	0.063	0.055	0.063	−0.150
C22:5n3 (DPA)	0.182	0.229	−0.185	−0.224	−0.316^*	−0.247	−0.151	−0.091	−0.090	0.185	−0.005	−0.096	0.048	0.072	−0.093	−0.108
C22:6n3 (DHA)	0.874	0.075	0.039	−0.117	−0.143	−0.227	−0.107	0.044	0.036	0.114	−0.147	0.008	0.011	−0.082	–.0810	–.0582
D5D	−0.233	−0.126	−0.035^**	−0.291^*	−0.179	−0.117	0.158	−0.366^**	−0.400^**	−0.056	−0.248	−0.302^*	−0.155	−0.240	−0.179	−0.228
D6D	0.191	0.191	0.365^**	0.048	−0.070	−0.078	−0.284^*	0.003	0.049	0.383^**	0.364^**	0.089	0.303^*	0.330^*	0.087	0.044
D9D	0.042	0.119	0.546^**	0.318^*	0.016	−0.097	−0.167	0.453^**	0.459^**	0.060	0.179	0.226	−0.020	0.196	0.236	0.127

Mean ± S.D.; Significantly correlated by pearson correlation analysis at *p <0.05, and **p <0.01 and respectively
AA Arachidonic acid, ALNA α-Linolenic acid, DGLA Dihomo-γ-linolenic acid, DHA Docosahexanoic acid, DPA Docosapentaenoic acid, DTA Docosatetraenoic acid, D5D delta-5-Desatuase (C20:4 ω-6/C20:3 ω-6), D6D delta-6-Desatuase(C18:3 ω-6/C18:2 ω-6), D9D delta-9-Desatuase(C18:1 ω-9/C18:0), EDA Eicosadienoic acid, EPA Eicosapentaenoic acid, GLA γ-linolenic acid, LA Linoleic acid, MUFA monosaturated fatty acid, PUFA polysaturated fatty acid, SFA saturated fatty acid, C22:5 ω-6(Docosapentaenoic acid, DPA) = osbond acid; C22:5 ω-3 (Docosapentaenoic acid, DPA) = clupanodonic acid, BMI body mass index, SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure, TG Triglyceride, TC total cholesterol, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein, cholesterol, AI (TC-HDL)/HDL, Apo B apolipoprotein B, FBS fasting blood sugar, HOMA-IR homeostasis model assessment of insulin resistance, hs-CRP high sensitivity C-reactive protein

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