Comparative chemical profiling, cholinesterase inhibitions and anti-radicals properties of essential oils from Polygonum hydropiper L: A Preliminary anti- Alzheimer’s study

Table 3 Antioxidant Potential of essential oils from Polygonum hydropiper leaves and flowers

Samples	DPPH free radical scavenging			ABTS free radical scavenging		H₂O₂ free radical scavenging
Samples	Conc. μg/ml	% inhibition	IC₅₀	% inhibition	IC₅₀	% inhibition	IC₅₀
Essential oils from leaves (Ph.LO)	12.5	37.95 ± 0.29***	20	9.66 ± 1.33^ns	180	25.66 ± 0.66 ^ns	60
	25	46.66 ± 0.72^ns		13.00 ± 1.15 ^ns		33.16 ± 1.01 ^ns
	50	53.50 ± 0.86^ns		25.66 ± 2.18 ^ns		42.50 ± 0.28 ^ns
	100	60.66 ± 0.92*		27.50 ± 0.28 ^ns		47.50 ± 1.04 ^ns
	200	65.16 ± 0.60*		42.66 ± 0.92 ^ns		58.00 ± 0.28 ^ns
	400	72.00 ± 1.04***		58.16 ± 1.09*		65.16 ± 1.96 ^ns
	800	79.50 ± 0.28***		73.16 ± 1.01***		70.66 ± 0.88 ^ns
	1000	85.00 ± 1.15**		89.00 ± 0.50***		79.00 ± 1.00***
Essential oils from Flower (Ph.FO)	12.5	22.83 ± 0.72***	200	30.00 ± 0.00 ^ns	45	21.83 ± 0.60 ^ns	50
	25	28.00 ± 0.57***		38.50 ± 0.86 ^ns		32.00 ± 2.30 ^ns
	50	35.83 ± 0.60***		45.16 ± 0.60 ^ns		40.83 ± 0.92 ^ns
	100	42.33 ± 0.44***		51.33 ± 0.66 ^ns		49.83 ± 0.44 ^ns
	200	47.33 ± 1.30***		66.00 ± 1.15 ^ns		58.50 ± 0.76 ^ns
	400	54.83 ± 2.92***		72.00 ± 0.86 ^ns		64.00 ± 0.00 ^ns
	800	70.16 ± 0.60***		78.66 ± 0.88***		71.66 ± 3.17*
	1000	81.33 ± 0.72***		87.33 ± 1.76***		77.16 ± 0.44***
Ascorbic Acid (Positive control)	12.5	45.00 ± 0.50	5	49.16 ± 0.60	10	46.66 ± 0.72	7
	25	47.33 ± 1.30		56.50 ± 1.04		55. 16 ± 0.60
	50	54.88 ± 1.30		63.16 ± 1.01		63.00 ± 0.00
	100	63.00 ± 1.15		70.00 ± 0.00		68.58 ± 0.69
	200	68.36 ± 0.57		75.45 ± 0.65		71.44 ± 0.58
	400	79.85 ± 2.24		81.37 ± 0.64		76.45 ± 0.77
	800	87.08 ± 0.47		88.37 ± 0.54		84.36 ± 0.64
	1000	91.90 ± 0.96		94.30 ± 0.61		89.37 ± 0.65

Each value represent mean ± S.E.M of three independent experimental results. Values significantly different when compared to slandered drug (Ascorbic acid) at the same concentration i.e. *: P < 0.05, **: P < 0.01 and ***: P < 0.001. ns: Values not significantly different in comparison to P. control

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