Skip to main content

Table 4 Lipid profile in total population, and in case and control groups according to rs5888 (C > T) genotypes in SCARB1 gene

From: The rs5888 single nucleotide polymorphism in scavenger receptor class B type 1 (SCARB1) gene and the risk of premature coronary artery disease: a case-control study

 

CC

CT

TT

P value*

All participants

(n = 357)

(n = 540)

(n = 154)

 Triglyceride (mg/dl)

183.6 ± 108.7

179.6 ± 113.7

192.5 ± 140.5

0.572

 HDL cholesterol (mg/dl)

41.8 ± 11.6

42.6 ± 12.1

41.4 ± 10.4

0.569

 LDL cholesterol (mg/dl)

119.5 ± 40.2

115.9 ± 40.3

114.9 ± 40.4

0.351

 Total cholesterol (mg/dl)

188.5 ± 51.1

186.2 ± 47.3

185.1 ± 47.2

0.691

Non-CAD group

(n = 195)

(n = 281)

(n = 70)

 Triglyceride (mg/dl)

175.7 ± 113.2

166.0 ± 99.0

196.4 ± 162.6

0.065

 HDL cholesterol (mg/dl)

43.5 ± 12.6

44.3 ± 11.0

43.8 ± 9.5

0.853

 LDL cholesterol (mg/dl)

120.6 ± 36.2

113.0 ± 34.6

118.2 ± 41.6

0.054

 Total cholesterol (mg/dl)

189.4 ± 44.0

183.8 ± 40.7

191.5 ± 46.6

0.108

CAD group

(n = 162)

(n = 259)

(n = 84)

 Triglyceride (mg/dl)

193.3 ± 102.5

194.2 ± 126.4

189.1 ± 119.4

0.887

 HDL cholesterol (mg/dl)

39.7 ± 10.0

40.8 ± 12. 9

39.3 ± 10.7

0.499

 LDL cholesterol (mg/dl)

118.2 ± 44.5

119.0 ± 45.4

112.0 ± 39.4

0.470

 Total cholesterol (mg/dl)

189.4 ± 58.9

188.8 ± 53.4

179.6 ± 47.5

0.350

  1. *Adjusted for age, sex, cigarette smoking, and body mass index (BMI)
  2. Data are presented as mean ± SD
  3. CAD, Coronary artery disease; SCARB1, scavenger receptor class B type 1