Table 5 Unadjusted and adjusted odds ratios for the effect of rs5888 genotypes on premature coronary artery disease in whole and in men and women separately

All participants

0.164

0.046

 CC

1.0 (Ref.)

-

1.0 (Ref.)

–

 CT

1.1 (0.9 to 1.5)

0.448

1.2 (0.9 to 1.6)

0.204

 TT

1.4 (1.0 to 2.1)

0.058

1.7 (1.1 to 2.6)

0.013

 CT + TT

1.2 (0.9 to 1.5)

0.214

1.3 (1.0 to 1.7)

0.077

 Allele T vs. C

1.2 (1.0 to 1.4)

0.082

1.3 (1.0 to 1.5)

0.020

Male sex

0.781

0.583

 CC

1.0 (Ref.)

–

1.0 (Ref.)

–

 CT

1.0 (0.7 to 1.5)

0.874

1.2 (0.8 to 1.8)

0.448

 TT

1.2 (0.7 to 2.1)

0.491

1.3 (0.7 to 2.5)

0.336

 CT + TT

1.1 (0.7 to 1.6)

0.715

1.2 (0.8 to 1.9)

0.348

 Allele T vs. C

1.1 (0.8 to 1.4)

0.544

1.2 (0.9 to 1.5)

0.311

Female sex

0.146

0.044

 CC

1.0 (Ref.)

–

1.0 (Ref.)

–

 CT

1.2 (0.8 to 1.7)

0.354

1.1 (0.7 to 1.8)

0.551

 TT

1.7 (1.0 to 2.9)

0.050

2.1 (1.2 to 4.0)

0.014

 CT + TT

1.3 (0.9 to 1.8)

0.167

1.3 (0.9 to 2.0)

0.202

 Allele T vs. C

1.2 (1.0 to 1.6)

0.070

1.3 (1.0 to 1.8)

0.037