The rs5888 single nucleotide polymorphism in scavenger receptor class B type 1 (SCARB1) gene and the risk of premature coronary artery disease: a case-control study

Table 6 The genotypes of rs5888 single nucleotide polymorphism in association with CAD severity

	CC (n = 357)	CT (n = 540)	TT (n = 154)	P-value	P-value^*
Vessel score, n (%)				0.178	0.247
0	195 (54.6)	281 (52.0)	70 (45.3)
1VD	72 (20.2)	117 (21.7)	46 (29.9)
2VD	40 (11.2)	74 (13.7)	22 (14.3)
3VD	50 (14.0)	68 (12.6)	16 (10.4)
Gensini score, median (25th to 75th percentiles), n^a.
All	42 (20 to 65), 162	42 (23 to 75), 259	37 (20 to 64), 84	0.449	0.572
Males	43 (26 to 77), 81	40 (23 to 67), 115	36 (25 to 61), 38	0.816	0.697
Females	40 (20 to 64), 81	45 (23 to 78), 144	38 (18 to 66), 46	0.233	0.398

0 no coronary lesion, 1VD one-vessel disease, 2VD Two-vessel disease, 3VD three-vessel disease, CAD coronary artery disease, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol
^* P-values adjusted for diabetes mellitus, cigarette smoking, opium addiction, hypertension, and family history of CAD as well as body mass index, serum HDL-C, triglyceride, and LDL-C
^aA total number of 505 patients after excluding 546 with normal coronary arteries (Gensini score = 0)

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