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Table 1 Demographic and laboratory characteristics of patients stratified by renal function

From: Apolipoprotein E polymorphism modulation of asymmetric dimethylarginine in hypertensive patients is determined by renal function

 

Group I

(N = 189)

Group II

(N = 222)

Group III

(N = 202)

p

Age (years)

60.0 ± 11.7

66.8 ± 11.6

52.4 ± 14.9

0.000**

Male

57 (30.5 %)

136 (61.3 %)

117 (58.2 %)

0.000***

Caucasian

105 (56.1 %)

145 (65.9 %)

138 (68.9 %)

0.000***

BMI (kg/cm2)

30.3 ± 6.2

28.6 ± 5.1

25.2 ± 2.6

0.000**

Waist circumference (cm)

98.3 ± 13.9

101.9 ± 13.5

95.6 ± 10.8a

0.004*

Diabetes mellitus

59 (32.6 %)

118 (53.4 %)

65 (32.5 %)

0.000***

Metabolic Syndrome

118 (64.1 %)

158 (71.8 %)

146 (73.0 %)

0.000***

Cardiovascular Disease

44 (24.6 %)

91 (41.9 %)

86 (43.7 %)

<.000***

o Cerebrovascular disease

20 (11.2 %)

26 (12.0 %)

21 (10.7 %)

0.912***

o Coronary disease

17 (9.5 %)

51 (23.5 %)

44 (22.3 %)

0.001***

o Peripheral vascular disease

11 (6.1 %)

18.9 (41.0 %)

46 (23.4 %)

0.000***

o Congestive heart failure

17 (9.5 %)

33 (15.3 %)

31 (15.7 %)

0.000***

Statin use

77/181 (40.7 %)

125/222 (54.3 %)

107/200 (53.2 %)

0.017***

Cholesterol(mM)

4.78 ± 0.93

4.65 ± 1.12

3.72 ± 1.00a.b

0.000*

HDL-C(mM)

1.27 ± 0.34

1.16 ± 0.33c

0.99 ± 0.37 a.b

0.000*

LDL-C(mM)

2.78 ± 0.82

2.64 ± 0.97

1.89 ± 0.74a.b

0.000*

Triglycerides(mM)

1.61 ± 0.90

1.80 ± 0.98

1.91 ± 1.31

0.023**

Creatinine(ÎŒM)

73.4 ± 15.9

175.0 ± 69.8

930.8 ± 284.6

0.000**

ADMA (ÎŒM)

0.48 ± 0.12

0.75 ± 0.31a

1.34 ± 0.90

0.000**

CRP (mg/dL)

0.49 ± 0.73

0.62 ± 0.83

1.47 ± 3.78

0.004**

  1. *ANOVA, **Kruskal-Wallis-one way- ANOVA, ***Pearson chi-square
  2. By post hoc Bonferroni test: agroups III and II, bgroups III and I, cgroups II and I