Skip to main content

Table 5 Demographic and laboratory characteristics of patients according to ADMA tertile

From: Apolipoprotein E polymorphism modulation of asymmetric dimethylarginine in hypertensive patients is determined by renal function

 

First tertile

(0.12 - 0.54) (N = 199)

Second tertile

(0.55 - 0.79) (N = 206)

Third tertile

(0.80 - 4.91) (N = 207)

P

Age (years)

62.37 ± 10.53

66.01 ± 11.95

65.64 ± 11.70

0.000**

Dialysis vintage (months)

2.48 ± 24.24

7.90 ± 1.48c

25.62 ± 1.92a,b

0.000**

Male

25 (21.6 %)

91 (78.4 %)

37 (19.7 %)

0.508***

Caucasian

31 (22.8 %)

105 (72.2 %)

51 (20.6 %)

0.440***

BMI (kg/cm2)

29.74 ± 5.55

29.11 ± 5.24

27.63 ± 13.43

0.000**

Waist circumference (cm)

99.46 ± 13.43

101.45 ± 11.40

101.88 ± 14.62

0.798*

Diabetes mellitus

15 (23.1 %)

50 (76.9 %)

32 (18.8 %)

0.895***

Metabolic syndrome

28 (19.4 %)

116 (80.6 %)

48 (17.8 %)

0.733***

Cardiovascular disease

66 (30.1 %)

77 (35.2 %)

76(34.7 %)

0.646***

o Cerebrovascular disease

0 (0.0 %)

20 (100.0 %)

13 (28.3 %)

0.073***

o Coronary disease

13 (29.5 %)

31 (70.5 %)

11 (16.9 %)

0.703***

o Peripheral vascular disease

22 (22.9 %)

35 (36.5 %)

39 (20.4 %)

0.697***

o Congestive heart failure

27 (34.2 %)

28 (35.4 %)

24 (30.4 %)

0.738***

Statin use

23 (21.9 %)

82 (78.1 %)

38 (19.4 %)

0.602***

Cholesterol(mM)

4.70 ± 1.08

4.45 ± 1.07c

4.59 ± 1.07a.b

0.000*

HDL-C(mM)

1.21 ± 0.34

1.05 ± 0.39

1.13 ± 0.36 a.b

0.000*

LDL-C(mM)

2,71 ± 0.92

2.53 ± 0.88

2.24 ± 2.24 a.b

0.000*

Triglycerides(mM)

1.99 ± 1.36

1.66 ± 1.14

1.84 ± 1.06

0.804**

Uric acid (mM)

0.36 ± 0.11

0.42 ± 0.12c

0.41 ± 0.10 b

0.000*

Creatinine(ÎŒM)

131.72 ± 81.33

845.10 ± 239.56c

947.65 ± 290.84a,b

0.000**

CRP (mg/dL)

0.50 ± 0.08

0.66 ± 0.21

0.50 ± 0.72

0.321**

  1. *ANOVA, **Kruskal-Wallis-one way- ANOVA, ***Pearson chi-square
  2. By post hoc Bonferroni test: a groups III and II, bgroups III and I, cgroups II and I