|
Control group
|
HFD group
|
Acipimox group
|
---|
Weeks
|
8 w
|
16 w
|
24 w
|
8 w
|
16 w
|
24 w
|
8 w
|
16 w
|
24 w
|
TC (mmol/L)
|
1.05 ± 0.16
|
1.17 ± 0.15
|
1.24 ± 0.15
|
1.36 ± 0.08
|
1.81 ± 0.13*#
|
1.93 ± 0.17*#
|
1.18 ± 0.08
|
1.22 ± 0.11
|
1.21 ± 0.16
|
TG (mmol/L)
|
0.25 ± 0.04
|
0.30 ± 0.05
|
0.38 ± 0.05
|
0.84 ± 0.07**##
|
1.13 ± 0.14**#
|
0.84 ± 0.08**#
|
0.44 ± 0.06
|
0.65 ± 0.08
|
0.50 ± 0.07
|
FFAs (mmol/L)
|
0.29 ± 0.07
|
0.29 ± 0.07
|
0.34 ± 0.06
|
0.43 ± 0.07
|
0.90 ± 0.06**##
|
0.91 ± 0.10**#
|
0.34 ± 0.05
|
0.32 ± 0.07
|
0.56 ± 0.10
|
- Data are shown as means ± SEM. *
p < 0.05 versus the corresponding Control group; **
p < 0.01 versus the corresponding Control group; #
p < 0.05 versus the corresponding Acipimox group; ##
p < 0.01 versus the corresponding Acipimox group, HFD, high-fat diet, TC, Total cholesterol, TG triglycerides, FFAs free fatty acids