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Table 3 Effect of rs9939609 on biochemical traits in the study subjects

From: Role of a common variant of Fat Mass and Obesity associated (FTO) gene in obesity and coronary artery disease in subjects from Punjab, Pakistan: a case control study

Group Parameter Genotype p-value
TT TA AA
Controls (n = 250) Total cholesterol (mmol/L) 4.38 ± 1.12 4.72 ± 1.36 4.67 ± 0.66 0.123
Triglycerides (mmol/L) 2.34 ± 0.66 2.16 ± 0.75 2.73 ± 1.22 0.109
HDLC (mmol/L) 1.80 ± 0.41 1.67 ± 0.15 1.65 ± 0.43 0.119
LDLC (mmol/L) 2.13 ± 0.41 2.25 ± 0.48 2.26 ± 0.55 0.187
FBG (mg/dL) 90.54 ± 6.81 90.81 ± 7.98 89.81 ± 5.41 0.019*
CAD (n = 425) Total cholesterol (mmol/L) 5.41 ± 1.41 5.30 ± 1.36 5.38 ± 1.37 0.735
Triglycerides (mmol/L) 2.35 ± 0.85 2.43 ± 0.81 2.41 ± 0.66 0.603
HDLC (mmol/L) 1.15 ± 0.32 1.18 ± 0.29 1.16 ± 0.30 0.795
LDLC (mmol/L) 2.73 ± 0.72 2.75 ± 0.73 2.71 ± 0.85 0.953
FBG (mg/dL) 97.14 ± 6.81 98. + 1 ± 5.98 100.41 ± 6.41 0.014*
Obese (n = 295) Total cholesterol (mmol/L) 5.50 ± 0.91 5.50 ± 0.74 5.49 ± 0.64 0.998
Triglycerides (mmol/L) 2.51 ± 0.76 2.46 ± 0.75 2.71 ± 1.05 0.405
HDLC (mmol/L) 1.11 ± 0.11 1.13 ± 0.11 1.07 ± 0.10 0.105
LDLC (mmol/L) 2.96 ± 0.56 3.04 ± 0.54 2.95 ± 0.58 0.552
FBG (mg/dL) 101.91 ± 13.52 104.21 ± 17.65 109.92 ± 16.54 0.001*
  1. The table shows a comparison of mean biochemical parameters for three different genotypes in the study groups with strength of effect indicated by the p-value. CAD Coronary Artery Heart group, HDL-C High Density Lipoprotein cholesterol, LDL-C Low Density Lipoprotein cholesterol, FBG fasting blood glucose,*indicates any significant association