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Table 1 Anthropometric and metabolic characteristics of subjects

From: SNPs in FNDC5 (irisin) are associated with obesity and modulation of glucose and lipid metabolism in Saudi subjects

  Group Sub-group
Variables T2DM Non-T2DM Obese Lean
  (N = 394) (N = 420) (N = 293) (N = 264)
Male/Female 234/160 188/232 121/172 150/114
Age (years) 53.5 ± 11.2 44.3 ± 12.7** 47.8 ± 11.12 48.4 ± 14.9
BMI (kg/m2) 29.5 ± 6.0 27.2 ± 5.3** 34.9 ± 4.39 21.7 ± 2.8**
Systolic BP (mmHg) 128.8 ± 15.1 117 ± 14.0** 125.4 ± 14.2 119 ± 14.3**
Diastolic BP (mmHg) 80.6 ± 9.2 77.1 ± 10.1** 79.7 ± 10.2 75.4 ± 7.7**
Total Cholesterol (mmol/l) 5.3 ± 1.17 5.0 ± 1.17** 5.18 ± 1.1 5.17 ± 1.2
Triglycerides (mmol/l) 1.7 ± 0.6 1.3 ± 0.56** 1.5 ± 0.57 1.45 ± 0.61*
Glucose (mmol/l) 10.1 ± 3.59 5.1 ± 0.93** 10.1 ± 3.59 5.1 ± 0.93*
HDL-Cholesterol (mmol/) 0.85 ± 0.34 0.92 ± 0.40* 0.90 ± 0.37 0.87 ± 0.39
LDL-Cholesterol (mmol/) 3.63 ± 1.0 3.56 ± 1.0 3.60 ± 1.0 3.56 ± 1.0
Insulin (μIU/mL) 15.08 ± 9.0 15.9 ± 9.1 17.6 ± 9.4 10.6 ± 6.3**
HOMA-IR 6.88 ± 5.5 3.7 ± 2.35** 6.35 ± 4.4 3.0 ± 2.1**
  1. Note: “**” denotes p < 0.001, “*” represents p < 0.01. Independent sample t-test was used to compute the difference between studied groups. Data were presented as mean ± standard deviation. Insulin and HOMA-IR are log transformed prior to analysis. Insulin and HOMA-IR values were available for 392 subjects