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Table 1 Anthropometric and metabolic characteristics of subjects

From: SNPs in FNDC5 (irisin) are associated with obesity and modulation of glucose and lipid metabolism in Saudi subjects

 

Group

Sub-group

Variables

T2DM

Non-T2DM

Obese

Lean

 

(N = 394)

(N = 420)

(N = 293)

(N = 264)

Male/Female

234/160

188/232

121/172

150/114

Age (years)

53.5 ± 11.2

44.3 ± 12.7**

47.8 ± 11.12

48.4 ± 14.9

BMI (kg/m2)

29.5 ± 6.0

27.2 ± 5.3**

34.9 ± 4.39

21.7 ± 2.8**

Systolic BP (mmHg)

128.8 ± 15.1

117 ± 14.0**

125.4 ± 14.2

119 ± 14.3**

Diastolic BP (mmHg)

80.6 ± 9.2

77.1 ± 10.1**

79.7 ± 10.2

75.4 ± 7.7**

Total Cholesterol (mmol/l)

5.3 ± 1.17

5.0 ± 1.17**

5.18 ± 1.1

5.17 ± 1.2

Triglycerides (mmol/l)

1.7 ± 0.6

1.3 ± 0.56**

1.5 ± 0.57

1.45 ± 0.61*

Glucose (mmol/l)

10.1 ± 3.59

5.1 ± 0.93**

10.1 ± 3.59

5.1 ± 0.93*

HDL-Cholesterol (mmol/)

0.85 ± 0.34

0.92 ± 0.40*

0.90 ± 0.37

0.87 ± 0.39

LDL-Cholesterol (mmol/)

3.63 ± 1.0

3.56 ± 1.0

3.60 ± 1.0

3.56 ± 1.0

Insulin (μIU/mL)

15.08 ± 9.0

15.9 ± 9.1

17.6 ± 9.4

10.6 ± 6.3**

HOMA-IR

6.88 ± 5.5

3.7 ± 2.35**

6.35 ± 4.4

3.0 ± 2.1**

  1. Note: “**” denotes p < 0.001, “*” represents p < 0.01. Independent sample t-test was used to compute the difference between studied groups. Data were presented as mean ± standard deviation. Insulin and HOMA-IR are log transformed prior to analysis. Insulin and HOMA-IR values were available for 392 subjects