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Table 4 Partial Least Square analysis (PLS); the association between tumor characteristics and lipoprotein subfractions by NMR

From: Lipoprotein subfractions by nuclear magnetic resonance are associated with tumor characteristics in breast cancer

Tumor Characteristic β-coefficient p-value
Progesterone receptor, %
 Total plasma Apolipoprotein A1, mg/dL 1.326 e-01 0.002
 ILDL Free Cholesterol, mg/dL −6.625 e-03 0.062
 ILDL Phospholipids, mg/dL −1.015 e-02 0.076
 HDL Cholesterol, mg/dL 9.019 e-02 8.522 e-06
 HDL Free Cholesterol, mg/dL 1.918 e-02 0.002
 HDL Phospholipids, mg/dL 1.206 e-01 1.138 e-04
 HDL Apolipoprotein A1, mg/dL 1.393 e-01 1.198 e-04
 VLDL4 Cholesterol, mg/dL −1.227 e-02 0.068
 VLDL4 Free Cholesterol, mg/dL −5.829 e-03 0.085
 VLDL4 Phospholipids, mg/dL −1.138 e-02 0.056
 HDL1 Cholesterol, mg/dL 4.957 e-02 0.014
 HDL1 Phospholipids, mg/dL 6.670 e-02 0.012
 HDL1 Apolipoprotein A1, mg/dL 7.637 e-02 0.022
 HDL1 Apolipoprotein A2, mg/dL 7.235 e-03 0.041
 HDL2 Free Cholesterol, mg/dL 3.600 e-03 0.040
 HDL2 Phospholipids, mg/dL 2.240 e-02 0.009
 HDL2 Apolipoprotein A1, mg/dL 2.479 e-02 0.012
 HDL3 Phospholipids, mg/dL 2.549 e-02 0.011
 HDL3 Apolipoprotein A1, mg/dL 2.906 e-02 0.016
Tumor grade 1–3
 Total plasma Triglycerides, mg/dL −2.694 e-03 0.011
 HDL Apolipoprotein A1, mg/dL −1.807 e-03 0.056
Ki67 %
 HDL Cholesterol, mg/dL −3.252 e-02 0.060
 HDL2 Cholesterol, mg/dL −7.904 e-03 0.083
Estrogen receptor, % No significant results
Nodal metastasis, no
  1. PLS Partial Least Square (3 components included). Significance level p < 0.05
  2. Abbreviations: HDL high-density lipoprotein, ILDL intermediar-low-density lipoprotein, LDL low-density lipoprotein, VLDL very-low-density lipoprotein