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Table 4 Partial Least Square analysis (PLS); the association between tumor characteristics and lipoprotein subfractions by NMR

From: Lipoprotein subfractions by nuclear magnetic resonance are associated with tumor characteristics in breast cancer

Tumor Characteristic

β-coefficient

p-value

Progesterone receptor, %

 Total plasma Apolipoprotein A1, mg/dL

1.326 e-01

0.002

 ILDL Free Cholesterol, mg/dL

−6.625 e-03

0.062

 ILDL Phospholipids, mg/dL

−1.015 e-02

0.076

 HDL Cholesterol, mg/dL

9.019 e-02

8.522 e-06

 HDL Free Cholesterol, mg/dL

1.918 e-02

0.002

 HDL Phospholipids, mg/dL

1.206 e-01

1.138 e-04

 HDL Apolipoprotein A1, mg/dL

1.393 e-01

1.198 e-04

 VLDL4 Cholesterol, mg/dL

−1.227 e-02

0.068

 VLDL4 Free Cholesterol, mg/dL

−5.829 e-03

0.085

 VLDL4 Phospholipids, mg/dL

−1.138 e-02

0.056

 HDL1 Cholesterol, mg/dL

4.957 e-02

0.014

 HDL1 Phospholipids, mg/dL

6.670 e-02

0.012

 HDL1 Apolipoprotein A1, mg/dL

7.637 e-02

0.022

 HDL1 Apolipoprotein A2, mg/dL

7.235 e-03

0.041

 HDL2 Free Cholesterol, mg/dL

3.600 e-03

0.040

 HDL2 Phospholipids, mg/dL

2.240 e-02

0.009

 HDL2 Apolipoprotein A1, mg/dL

2.479 e-02

0.012

 HDL3 Phospholipids, mg/dL

2.549 e-02

0.011

 HDL3 Apolipoprotein A1, mg/dL

2.906 e-02

0.016

Tumor grade 1–3

 Total plasma Triglycerides, mg/dL

−2.694 e-03

0.011

 HDL Apolipoprotein A1, mg/dL

−1.807 e-03

0.056

Ki67 %

 HDL Cholesterol, mg/dL

−3.252 e-02

0.060

 HDL2 Cholesterol, mg/dL

−7.904 e-03

0.083

Estrogen receptor, %

No significant results

Nodal metastasis, no

  1. PLS Partial Least Square (3 components included). Significance level p < 0.05
  2. Abbreviations: HDL high-density lipoprotein, ILDL intermediar-low-density lipoprotein, LDL low-density lipoprotein, VLDL very-low-density lipoprotein