Skip to main content

Table 1 Clinical and biochemical characteristics of primary HTG and control groupsa

From: Frequency of rare mutations and common genetic variations in severe hypertriglyceridemia in the general population of Spain

  Primary HTG Control p
  N = 73 N = 90  
Age, years 56.4 ± 12.0 53.5 ± 16.2 0.210
Males, n (%) 58 (79.4) 45 (50.0) 0.000
Body mass index, kg/m2 27.6 ± 2.35 26.6 ± 3.25 0.044
Total cholesterol, mg/dL 264 ± 48.0 196 ± 34.1 0.000
Triglycerides, mg/dL 654 (550–810) 63.0 (49.7–74.0) 0.000
HDL cholesterol, mg/dL 40.1 ± 10.5 55.2 ± 12.6 0.000
Glucose, mg/dL 100 ± 16.1 91.3 ± 12.7 0.000
Hb1Ac (%) 5.6 (5.3–6.15) 5.3 (5.1–5.5) 0.000
Diabetes, n (%) 18 (24.7) 2 (2.3) 0.000
Hypertension, n (%) 31 (42.5) 13 (14.4) 0.000
Cardiovascular disease, n (%) 11 (15.1) 3 (3.3) 0.005
APOE genotype (%)    0.000
 ε2- ε2 0 0  
 ε2- ε3 19.7 0  
 ε3- ε3 57.7 100  
 ε3- ε4 16.9 0  
 ε4- ε4 1.4 0  
 ε4- ε2 4.2 0  
  1. Quantitative variables are expressed as mean ± standard deviation, except for variables not following normal distribution, expressed as median (interquartile range). Qualitative variables are expressed as %. The p value was calculated by Student’s t test, Mann–Whitney U and Chi - square as appropriate.
  2. aLipid values refer to the most recent values without lipid-lowering treatment