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Table 1 Clinical and biochemical characteristics of primary HTG and control groupsa

From: Frequency of rare mutations and common genetic variations in severe hypertriglyceridemia in the general population of Spain

 

Primary HTG

Control

p

 

N = 73

N = 90

 

Age, years

56.4 ± 12.0

53.5 ± 16.2

0.210

Males, n (%)

58 (79.4)

45 (50.0)

0.000

Body mass index, kg/m2

27.6 ± 2.35

26.6 ± 3.25

0.044

Total cholesterol, mg/dL

264 ± 48.0

196 ± 34.1

0.000

Triglycerides, mg/dL

654 (550–810)

63.0 (49.7–74.0)

0.000

HDL cholesterol, mg/dL

40.1 ± 10.5

55.2 ± 12.6

0.000

Glucose, mg/dL

100 ± 16.1

91.3 ± 12.7

0.000

Hb1Ac (%)

5.6 (5.3–6.15)

5.3 (5.1–5.5)

0.000

Diabetes, n (%)

18 (24.7)

2 (2.3)

0.000

Hypertension, n (%)

31 (42.5)

13 (14.4)

0.000

Cardiovascular disease, n (%)

11 (15.1)

3 (3.3)

0.005

APOE genotype (%)

  

0.000

 ε2- ε2

0

0

 

 ε2- ε3

19.7

0

 

 ε3- ε3

57.7

100

 

 ε3- ε4

16.9

0

 

 ε4- ε4

1.4

0

 

 ε4- ε2

4.2

0

 
  1. Quantitative variables are expressed as mean ± standard deviation, except for variables not following normal distribution, expressed as median (interquartile range). Qualitative variables are expressed as %. The p value was calculated by Student’s t test, Mann–Whitney U and Chi - square as appropriate.
  2. aLipid values refer to the most recent values without lipid-lowering treatment