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Table 7 Litter development, milk curd fat content and tocopherol concentration in milk curd and tissues of pups nursed by dams fed either a control or a CLA-supplemented dietd

From: Conjugated linoleic acid influences the metabolism of tocopherol in lactating rats but has little effect on tissue tocopherol concentrations in pups

Day after birth 1 7 14   P value
Treatment group Control CLA Control CLA Control CLA SEM Treatment Time tr.*time
Performance of pups
 Litter weight, g 56.4a 57.7a 143b 149b 264c 272c 3.35 0.36 <0.001 0.48
 Pup weight, g 7.1a 7.2a 17.9b 18.6b 38.2c 39.2c 0.46 0.39 <0.001 0.60
 Liver weights and liver triglyceride concentrations
 Liver, g/100 g BW 4.62a 4.80a NA NA 3.10b 3.32b 0.13 0.30 <0.001 0.92
 Liver TG, μmol/g liver 32.6 48.5 NA NA 40.9 36.7 3.28 0.21 0.69 0.032
Fat content
 Milk curd, μmol/g 299 312 327 292 329 301 6.40 0.059 0.51 0.015
Tocopherol concentration
 Milk curd, nmol/g 500a 429a 57.5b 55.6b 65.5b 59.8b 11.4 0.084 <0.001 0.077
 Liver, nmol/g 381a 320a 121b 102b 102b 91b 19.2 0.21 <0.001 0.67
 Lung, nmol/g 35.8a 39.3a 72.1b 67.9b 65.6b 71.0b 2.39 0.62 <0.001 0.24
 Adipose tissue, nmol/g NA NA 52.2a 50.9a 49.0a 71.9b 2.46 0.001 0.002 <0.001
  1. a-cMeans with superscripts without a common letter differ at P < 0.05. dValues are means after standardization to 8 pups per litter, n = 12–14. Means with superscripts without a common letter differ at P < 0.05. tr., treatment. NA, not analysed. Data were analysed by two-way ANOVA with treatment, time and their interaction as fixed effects and animal as random effect