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Table 7 Litter development, milk curd fat content and tocopherol concentration in milk curd and tissues of pups nursed by dams fed either a control or a CLA-supplemented dietd

From: Conjugated linoleic acid influences the metabolism of tocopherol in lactating rats but has little effect on tissue tocopherol concentrations in pups

Day after birth

1

7

14

 

P value

Treatment group

Control

CLA

Control

CLA

Control

CLA

SEM

Treatment

Time

tr.*time

Performance of pups

 Litter weight, g

56.4a

57.7a

143b

149b

264c

272c

3.35

0.36

<0.001

0.48

 Pup weight, g

7.1a

7.2a

17.9b

18.6b

38.2c

39.2c

0.46

0.39

<0.001

0.60

 Liver weights and liver triglyceride concentrations

 Liver, g/100 g BW

4.62a

4.80a

NA

NA

3.10b

3.32b

0.13

0.30

<0.001

0.92

 Liver TG, μmol/g liver

32.6

48.5

NA

NA

40.9

36.7

3.28

0.21

0.69

0.032

Fat content

 Milk curd, μmol/g

299

312

327

292

329

301

6.40

0.059

0.51

0.015

Tocopherol concentration

 Milk curd, nmol/g

500a

429a

57.5b

55.6b

65.5b

59.8b

11.4

0.084

<0.001

0.077

 Liver, nmol/g

381a

320a

121b

102b

102b

91b

19.2

0.21

<0.001

0.67

 Lung, nmol/g

35.8a

39.3a

72.1b

67.9b

65.6b

71.0b

2.39

0.62

<0.001

0.24

 Adipose tissue, nmol/g

NA

NA

52.2a

50.9a

49.0a

71.9b

2.46

0.001

0.002

<0.001

  1. a-cMeans with superscripts without a common letter differ at P < 0.05. dValues are means after standardization to 8 pups per litter, n = 12–14. Means with superscripts without a common letter differ at P < 0.05. tr., treatment. NA, not analysed. Data were analysed by two-way ANOVA with treatment, time and their interaction as fixed effects and animal as random effect