Table 1 Levels of 8-isoprostane and CysLTs in autistic patients compared to control participants
Parameters | Group | N | Mean ± S.D. | P value |
|---|---|---|---|---|
8-Isoprostane (pg/ml) | Control | 40 | 24.03 ± 2.65 | 0.001* |
Autistic Patients | 44 | 103.27 ± 12.56 | ||
Autism (severe in CARS) | 21 | 102.09 ± 11.11 | 0.556** | |
Autism (mild to moderate in CARS) | 23 | 104.35 ± 13.91 | ||
Autism (severe in SRS) | 5 | 103.35 ± 12.47 | 0.741** | |
Autism (mild to moderate in SRS) | 16 | 101.19 ± 12.60 | ||
Autism (mild to moderate in sensory) | 24 | 97.66 ± 12.65 | 0.001** | |
Autism (severe in sensory) | 17 | 111.17 ± 8.67 | ||
Age (less than 7) | 23 | 107.08 ± 12.19 | 0.034** | |
Age (more than 7) | 21 | 99.10 ± 11.86 | ||
Cysteinyl leukotrienes (ng/ml) | Control | 20 | 0.394 ± 0.108 | 0.001* |
Autistic Patients | 29 | 0.658 ± 0.199 | ||
Autism (mild to moderate in CARS) | 11 | 0.642 ± 0.197 | 0.738** | |
Autism (severe in CARS) | 18 | 0.668 ± 0.205 | ||
Autism (mild to moderate in SRS) | 1 | 0.602 ± 0.000 | 0.382** | |
Autism (severe in SRS) | 9 | 0.759 ± 0.161 | ||
Autism (mild to moderate in sensory) | 19 | 0.573 ± 0.156 | 0.001** | |
Autism (severe in sensory) | 10 | 0.821 ± 0.170 | ||
Age (less than 7) | 15 | 0.708 ± 0.210 | 0.164** | |
Age (more than 7) | 14 | 0.605 ± 0.177 |