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Table 4 Reduction in waist and hip circumference in Meratrim and placebo groups over 16 week study period

From: Efficacy and tolerability of Meratrim for weight management: a randomized, double-blind, placebo-controlled study in healthy overweight human subjects

Parameter Reduction

Weeks

Placebo

Meratrim

Net reductiona,b

P value

(n = 28)

(n = 29)

Waist size (cm)

2

1.07 ± 0.34

1.45 ± 0.25

0.38 (0.4 %)

0.339

4

2.18 ± 20.39

3.38 ± 0.37

1.20 (1.2 %)

0.016*

8

2.82 ± 0.53

5.14 ± 0.49

2.32 (2.3 %)

0.001*

12

3.29 ± 0.58

6.83 ± 0.58

3.54 (3.5 %)

<0.001*

16

3.71 ± 0.70

9.97 ± 0.73

6.26 (6.2 %)

<0.001*

Hip size (cm)

2

1.04 ± 0.27

1.62 ± 0.26

0.58 (0.5 %)

0.109

4

2.21 ± 0.37

3.14 ± 20.41

0.93 (0.9 %)

0.035*

8

3.61 ± 0.55

4.45 ± 20.51

0.84 (0.8 %)

0.112

12

4.32 ± 0.58

6.55 ± 0.63

2.23 (2.1 %)

0.002*

16

5.11 ± 0.69

10.38 ± 0.85

5.27 (4.9 %)

<0.0001*

  1. Values represent mean ± SE
  2. *Significant difference between Meratrim and placebo group mean values calculated using ANCOVA with baseline as covariate
  3. aNet reduction = Meratrim minus placebo
  4. bNumbers in parenthesis represents the % net reduction from baseline for Meratrim group