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Table 5 Changes in biochemical parameters after 16 weeks of supplementation

From: Efficacy and tolerability of Meratrim for weight management: a randomized, double-blind, placebo-controlled study in healthy overweight human subjects

Parameter Placebo Meratrim P value
(n = 28) (n = 29)
Liver function
 SGOT (U/L) −1.89 ± 0.83 −1.66 ± 0.97 0.2999
 SGPT (U/L) −2.22 ± 0.85 −3.65 ± 0.94 0.0181
Renal function
 BUN (mg/dL) −1.48 ± 0.26 −1.65 ± 0.29 0.1938
 Creatinine (mg/dL) −0.15 ± 0.03 −0.15 ± 0.03 0.7998
Metabolic panel
 Triglycerides (mg/dL) −13.68 ± 5.17 −43.62 ± 6.74 <0.001*
 Cholesterol (mg/dL) −0.75 ± 5.10 −20.00 ± 2.88 0.0002*
 LDL (mg/dL) 6.25 ± 4.79 −14.79 ± 2.93 <0.0001*
 HDL (mg/dL) -1.96±0.48 2.03±0.75 <0.0001*
 LHR 0.35 ± 0.14 −0.49 ± 0.11 <0.0001*
 VLDL (mg/dL) −5.04 ± 1.16 −7.24 ± 1.08 0.011*
 Fasting glucose (mg/dL) −10.64 ± 2.05 −9.41 ± 1.13 0.8926
  1. Values represent mean ± SE
  2. BUN Blood Urea Nitrogen, SGOT Serum Glutamic Oxaloacetic Transaminase; SGPT Serum Glutamic-Pyruvic Transaminase; LDL low-density lipoproteins; HDL high-density lipoprotein; LHR LDL/HDL ratio; VLDL very low-density lipoproteins
  3. *Significant difference between Meratrim and placebo group mean values calculated using ANCOVA with baseline as covariate