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Table 1 Clinical characteristics of healthy control and T2DM patients

From: A single-nucleotide polymorphism C-724 /del in the proter region of the apolipoprotein M gene is associated with type 2 diabetes mellitus

 

Healthy control

N = 76

T2DM

N = 259

P-value

N (male/femal)

40/36

149/110

0.450

AGE (yrs)

56.24 ± 8.59

56.33 ± 11.49

0.940

SBP (mmHg)

117.36 ± 12.79

137.71 ± 20.89

0.000

DBP (mmHg)

76.00 ± 7.79

83.44 ± 11.40

0.000

Cr (umol/L)

64.80 ± 14.61

75.03 ± 31.73

0.000

CYS-C (mg/L)

0.97 ± 0.21

1.17 ± 0.50

0.000

SOD (U/mL)

106.70 ± 10.69

82.01 ± 25.78

0.000

FPG (mmol/L)

5.36 ± 0.36

9.45 ± 3.33

0.000

TC (mmol/L)

4.26 ± 0.52

4.46 ± 1.22

0.038

TG (mmol/L)

1.18 ± 0.42

2.19 ± 1.89

0.000

HDL-C (mmol/L)

1.41 ± 0.20

1.21 ± 0.32

0.000

LDL-C (mmol/L)

2.31 ± 0.41

2.53 ± 0.80

0.002

apoA-I (g/L)

1.66 ± 0.26

1.29 ± 0.34

0.000

apoB (g/L)

0.75 ± 0.18

0.90 ± 0.33

0.000

LP (a) (mg/L)

131.51 ± 113.31

157.07 ± 191.36

0.269

apoM (ng/uL)

24.48 ± 11.45

20.17 ± 10.03

0.004

  1. Data mean ± SD
  2. N number, M male, F female, SBP systolic blood pressure, DBP diastolic blood pressure, Cr creatinine, CYS-C cystatin c, SOD superoxide dismutase, FBG fasting blood glucose, TG triglycerides, TC total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, apo apolipoprotein, LP (a) Lipoprotein (a)