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Table 3 C-724del. Genotype and clinical characteristics of T2DM patients and healthy control

From: A single-nucleotide polymorphism C-724 /del in the proter region of the apolipoprotein M gene is associated with type 2 diabetes mellitus

 

Healthy control

T2DM

P-value

CC

C/- + −/−

CC

C/- + −/−

CC vs. (C/- + −/−) in healthy control

CC vs. (C/- + −/−) in T2DM patients

N (male/femal)

40/33

0/3

131/87

18/13

0.203

0.949

AGE (yrs)

52.67 ± 4.93

56.54 ± 7.68

56.26 ± 11.24

56.81 ± 13.14

0.392

0.830

SBP (mmHg)

110.00 ± 10.00

117.81 ± 13.15

137.93 ± 20.45

136.06 ± 24.20

0.314

0.641

DBP (mmHg)

74.00 ± 4.00

76.00 ± 8.07

83.64 ± 11.40

81.97 ± 11.44

0.672

0.444

DM duration (yrs)

  

6.55 ± 5.87

6.41 ± 5.61

 

0.895

HbA1c (%)

  

9.56 ± 2.50

9.58 ± 2.37

 

0.960

Cr (umol/L)

50.50 ± 9.03

65.01 ± 14.63

75.13 ± 32.65

74.30 ± 24.27

0.094

0.891

CYS-C (mg/L)

0.86 ± 0.10

0.98 ± 0.22

1.18 ± 0.51

1.15 ± .38

0.362

0.798

SOD (U/mL)

107.67 ± 15.50

106.87 ± 10.29

82.63 ± 25.96

77.42 ± 24.34

0.898

0.292

FPG (mmol/L)

5.19 ± 0.33

5.37 ± 0.37

9.43 ± 3.35

9.59 ± 3.22

0.409

0.807

TC (mmol/L)

4.20 ± 0.16

4.28 ± 0.52

4.52 ± 1.25

4.05 ± .93

0.779

0.046

TG (mmol/L)

0.64 ± 0.11

1.20 ± 0.41

2.22 ± 1.95

1.98 ± 1.35

0.022

0.503

HDL-C (mmol/L)

1.49 ± 0.11

1.42 ± 0.19

1.22 ± 0.31

1.19 ± 0.37

0.560

0.706

LDL-C (mmol/L)

2.42 ± 0.07

2.31 ± 0.41

2.55 ± 0.80

2.32 ± 0.74

0.125

0.119

ApoA-I (g/L)

1.63 ± 0.11

1.68 ± 0.26

1.30 ± 0.34

1.22 ± 0.32

0.748

0.210

ApoB (g/L)

0.71 ± 0.09

0.75 ± 0.18

0.91 ± 0.34

0.83 ± 0.29

0.706

0.228

LP (a) (mg/L)

210.37 ± 54.13

129.60 ± 115.45

157.20 ± 199.35

156.10 ± 119.13

0.234

0.976

apoM (ng/uL)

23.63 ± 8.80

24.93 ± 11.78

20.44 ± 10.21

18.20 ± 8.53

0.851

0.245

  1. Data are means ± SD. P-Value <0.05 was shown in bold
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Lipids in Health and Disease

ISSN: 1476-511X