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Table 2 Serum fatty acid concentration according to the extent of coronary lesion

From: The relationship of the oleic acid level and ECHDC3 mRNA expression with the extent of coronary lesion

Fatty acids (%)

Total (n = 59)

Without lesion (n = 18)

Low lesion (n = 17)

Intermediate lesion (n = 17)

Major lesion (n = 7)

p-value

SFA

44.12 ± 3.85

44.70 ± 4.18

43.79 ± 4.46

43.93 ± 2.74

43.93 ± 4.40

0.904

Myristic (C14:0)

0.89 ± 0.30

0.94 ± 0.36

0.91 ± 0.26

0.87 ± 0.31

0.80 ± 0.19

0.756

Palmitic (C16:0)

30.83 ± 3.07

31.40 ± 2.95

30.61 ± 3.15

30.52 ± 2.80

30.63 ± 4.22

0.830

Stearic (C18:0)

12.40 ± 1.89

12.36 ± 2.15

12.27 ± 2.10

12.54 ± 1.70

12.50 ± 1.30

0.979

MUFA

24.87 ± 3.10

23.66 ± 2.88

25.97 ± 2.84a

25.77 ± 2.96b

23.14 ± 3.35

0.032

Palmitoleic (C16:1)

2.55 ± 0.75

2.41 ± 0.62

2.73 ± .63

2.56 ± 0.89

2.47 ± 0.98

0.658

Oleic (C18:1)

22.32 ± 2.77

21.25 ± 2.54

23.24 ± 2.48c

23.22 ± 2.73d

20.66 ± 2.89

0.027

PUFA

31.01 ± 4.78

31.65 ± 4.46

30.24 ± 5.37

30.30 ± 3.99

32.94 ± 6.01

0.529

n-6

26.77 ± 4.29

27.26 ± 3.66

25.96 ± 5.13

26.46 ± 3.54

28.26 ± 5.53

0.628

Linoleic (C18:2)

18.06 ± 3.84

18.64 ± 3.29

17.23 ± 4.35

18.10 ± 3.30

18.47 ± 5.39

0.742

Arachidonic (C20:4)

8.71 ± 2.37

8.62 ± 1.73

8.73 ± 2.47

8.36 ± 2.20

9.78 ± 3.89

0.620

n-3

4.23 ± 1.17

4.38 ± 1.56

4.29 ± 1.02

3.84 ± 0.86

4.68 ± 0.91

0.363

a-linolenic (C18:3)

0.54 ± 0.20

0.56 ± 0.20

0.53 ± 0.21

0.52 ± 0.16

0.57 ± 0.31

0.916

EPA (C20:5)

0.46 ± 0.18

0.53 ± 0.24

0.42 ± 0.15

0.43 ± 0.16

0.52 ± 0.11

0.223

DPA (C22:5)

0.83 ± 0.23

0.83 ± 0.21

0.86 ± 0.17

0.80 ± 0.28

0.85 ± 0.33

0.891

DHA (C22:6)

2.39 ± 0.93

2.46 ± 1.26

2.48 ± 0.82

2.10 ± 0.67

2.74 ± 0.73

0.410

n-6/n-3

6.77 ± 2.12

6.80 ± 1.93

6.61 ± 2.96

7.14 ± 1.63

6.16 ± 1.29

0.765

SCD16

0.08 ± 0.02

0.08 ± 0.02

0.09 ± 0.02

0.08 ± 0.02

0.08 ± 0.03

0.398

SCD18

1.85 ± 0.40

1.77 ± 0.38

1.95 ± 0.38

1.90 ± 0.45

1.68 ± 0.36

0.376

  1. Data are presented as mean ± standard deviation. Comparisons were performed by ANOVA way test followed by test t between pairs. P-values < 0.05 were considered statistically significant for all statistical test
  2. EPA, eicosapentaenoic, DHA docosahexaenoic, DPA docosapentaenoic SFA saturated fatty acid, MUFA monounsaturated fatty acid, PUFA polyunsaturated fatty acid, n6 omega-6, n3 omega-3, SCD16 stearoyl-CoA-Desaturase 16, SCD18, stearoyl-CoA-Desaturase 18
  3. a p = 0.023 for comparison between low lesion vs. without lesion groups by test t
  4. b p = 0.040 for comparison between intermediate lesion vs. without lesion groups by test t
  5. c p = 0.025 comparison between low lesion vs. without lesion groups by test t
  6. d p = 0.034 for comparison between intermediate lesion vs. without lesion groups by test t
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Lipids in Health and Disease

ISSN: 1476-511X