Fig. 3
From: Hepatitis B virus inhibits apolipoprotein A5 expression through its core gene
HBV inhibited ApoA5 promoter activity, mRNA and protein expression. a Effect of HBV on ApoA5 promoter activity, *P < 0.005. HepG2 cells were cotransfected with pHBV1.3 and the ApoA5 gene promoter pGL-ApoA5-LUC plasmid, and transfection with pBlue-ks was used as a control, the luciferase activity was measured at 48 h post-transfection. b and c Effects of HBV on ApoA5 mRNA expression. HepG2 cells were transfected with pHBV1.3 or pBlue-ks, 48 h after transfection, ApoA5 mRNA was determined by RT-PCR. d and e Effects of HBV on ApoA5 protein expression. HepG2 cells were transfected with pHBV1.3 or pBlue-ks, 48 h after transfection, ApoA5 protein was determined by western blotting