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Table 3 Non-lipid variables and lipid levels of the CHD patients by the APOA5 rs662799 genotypes

From: The APOA5 rs662799 polymorphism is associated with dyslipidemia and the severity of coronary heart disease in Chinese women

 

Men

Women

TT genotype (n = 103)

CT genotype (n = 90)

CC genotype (n = 12)

P

TT genotype (n = 63)

CT genotype (n = 51)

CC genotype (n = 6)

P

Non-lipid variables

 Age, years

64.97 ± 9.34

64.17 ± 10.00

65.17 ± 7.60

0.827

65.17 ± 7.49

63.82 ± 9.20

62.40 ± 9.29

0.589

 Weight, kg

65.71 ± 8.27

65.57 ± 9.13

64.00 ± 7.05

0.822

59.07 ± 8.14

58.59 ± 10.35

66.17 ± 5.63

0.156

 BMI, kg/m2

24.17 ± 3.02

23.86 ± 3.10

23.81 ± 2.74

0.762

24.15 ± 3.06

24.55 ± 4.48

26.59 ± 1.83

0.298

 Menopause, n (%)

NA

NA

NA

 

62 (98.41)

48 (94.12)

5 (83.33)

0.068

 Hypertension, n (%)

57 (55.34)

55 (61.11)

5 (41.47)

0.988

42 (66.7)

23 (45.10)

3 (50.00)

0.065

 Diabetes, n (%)

16 (15.53)

10 (11.11)

1 (8.33)

0.303

13 (20.6)

9 (17.65)

1 (16.67)

0.674

Lipid variables

 TG, mmol/L

1.36 ± 0.74

1.76 ± 1.73

1.83 ± 0.91

0.073

1.51 ± 0.86

1.96 ± 1.27

3.01 ± 1.55

0.009

 TC, mmol/L

4.08 ± 1.18

4.24 ± 1.29

3.82 ± 0.84

0.448

4.31 ± 1.23

4.48 ± 1.03

4.44 ± 1.22

0.722

 LDL-C, mmol/L

2.57 ± 0.91

2.71 ± 1.03

2.30 ± 0.61

0.307

2.70 ± 1.03

2.82 ± 0.79

2.94 ± 1.04

0.749

 HDL-C, mmol/L

0.96 ± 0.20

0.95 ± 0.23

0.82 ± 0.24

0.124

1.09 ± 0.24

1.03 ± 0.24

0.91 ± 0.24

0.149

 ApoAI, g/L

1.00 ± 0.16

1.02 ± 0.20

1.00 ± 0.15

0.861

1.13 ± 0.16

1.08 ± 0.20

1.11 ± 0.18

0.234

 ApoB, g/L

0.80 ± 0.30

0.83 ± 0.30

0.77 ± 0.19

0.618

0.80 ± 0.27

0.88 ± 0.26

0.83 ± 0.33

0.255

 Lp(a), mg/L

328.47 ± 362.37

271.98 ± 285.15

412.95 ± 371.18

0.271

369.27 ± 374.08

258.82 ± 274.92

441.90 ± 437.05

0.164

 TG/HDL-C

1.53 ± 1.04

1.98 ± 1.81

2.60 ± 1.78

0.057

1.52 ± 1.00

2.14 ± 2.02

3.83 ± 2.73

0.006

 TC/HDL-C

4.40 ± 1.41

4.59 ± 1.30

4.86 ± 1.17

0.411

4.07 ± 1.27

4.53 ± 1.33

4.99 ± 1.19

0.080

 LDL-C/HDL-C

2.80 ± 1.16

2.95 ± 1.09

2.90 ± 0.68

0.665

2.57 ± 1.08

2.88 ± 1.07

3.26 ± 0.86

0.150

 ApoB/apoAI

0.85 ± 0.45

0.87 ± 0.51

0.78 ± 0.19

0.808

0.72 ± 0.26

0.84 ± 0.29

0.86 ± 0.29

0.057

  1. CHD coronary heart disease, BMI body mass index, NA not available, TG triglycerides, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, apoAI apolipoprotein AI, apoB apolipoprotein B