Postprandial serum endotoxin in healthy humans is modulated by dietary fat in a randomized, controlled, cross-over study

Table 2 Treatment meal composition

	Low-fat		High fat (n-3)		High fat (n-6)		High fat (saturated)
Carbohydrate (%)^a	65		50		50		50
Protein (%)	15		15		15		15
Total fat (%)	20		35		35		35
Saturated fat (%)	5		10		10		15
Total n-6 fatty acids (%)	2		2		7		2
EPA + DHA fatty acids (%)	0		0.5		0		0
	Mean	SEM	Mean	SEM	Mean	SEM	Mean	SEM
Energy (kcal/g)^b	4.96^a	0.04	4.90^a	0.01	5.09^a	0.05	5.22^b	0.01
Endotoxin (EU/g)^b	89.66^a	3.29	72.97^b	1.07	72.72^b	0.63	65.98^c	0.51

^a Values (%) are based on 25 % of participant estimated daily energy requirements
^b Each test meal was bombed in duplicate as described in Methods. Test meals were assayed in duplicate using LAL kinetic chromogenic endotoxin assay. Values within the same row but with different superscript letters are significant at the p < 0.05 level

ISSN: 1476-511X