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Fig. 5 | Lipids in Health and Disease

Fig. 5

From: Myeloperoxidase-oxidized high density lipoprotein impairs atherosclerotic plaque stability by inhibiting smooth muscle cell migration

Fig. 5

PD98059, but not LY294002, reverses inhibitory effects of oxHDL on SMC migraiton. a SMCs were preincubated with in the presence or absence of LY294002 (50 μM) or PD98059 (10 μM) for 12 h. Then cells were treated with HDL for 5 min, cell lysates were analyzed by western blot. b LY294002 and PD98059 were applied 12 h before transwell experiments were performed. The migrating cells were stained and photographed after 12 h incubation. c The number of migrated cells were counted and compared, normalized to the number of migrated cells in non-treated HDL group (**p < 0.01 compared with HDL groups in each treatments)

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Lipids in Health and Disease

ISSN: 1476-511X