Association of the SPTLC3 rs364585 polymorphism and serum lipid profiles in two Chinese ethnic groups

Zhang, Qing-Hui; Yin, Rui-Xing; Gao, Hui; Huang, Feng; Wu, Jin-Zhen; Pan, Shang-Ling; Lin, Wei-Xiong; Yang, De-Zhai

doi:10.1186/s12944-016-0392-3

Lipids in Health and Disease

Table 6 The risk factors for serum lipid parameters in the males and females of the Han and Jing populations

From: Association of the SPTLC3 rs364585 polymorphism and serum lipid profiles in two Chinese ethnic groups

Lipid	Risk factor	B	Std.error	Beta	t	P
Han/male
TC	Glucose	0.224	0.036	0.295	6.291	0.000
	Pulse pressure	0.001	0.000	0.114	2.444	0.015
	Diastolic blood pressure	0.009	0.004	0.110	2.357	0.019
	Cigarette smoking	−0.089	0.042	−0.100	−2.123	0.034
TG	Waist circumference	0.049	0.010	0.405	4.765	0.000
	Cigarette smoking	0.219	0.052	0.201	4.182	0.000
	Glucose	0.168	0.044	0.181	3.770	0.000
	Diastolic blood pressure	0.014	0.005	0.142	2.998	0.003
	Age	−0.013	0.004	−0.146	−2.823	0.005
	Weight	−0.023	0.010	−0.198	−2.256	0.025
HDL-C	Waist circumference	−0.021	0.003	−0.307	−6.068	0.000
	Alcohol consumption	0.129	0.031	0.217	4.171	0.000
	Cigarette smoking	−0.128	0.031	−0.213	−4.164	0.000
	Genotype	−0.138	0.059	−0.111	−2.347	0.019
	Height	0.011	0.005	0.109	2.244	0.025
	Diastolic blood pressure	0.005	0.003	0.101	2.061	0.040
LDL-C	Glucose	0.095	0.019	0.241	5.060	0.000
	Genotype	0.165	0.046	0.170	3.570	0.000
	Diastolic blood pressure	0.005	0.002	0.111	2.324	0.021
ApoA1	Alcohol consumption	0.082	0.011	0.366	7.783	0.000
ApoA1	Waist circumference	−0.005	0.001	−0.196	−4.153	0.000
ApoB	Waist circumference	0.005	0.001	0.184	3.767	0.000
	Systolic blood pressure	0.002	0.001	0.179	3.513	0.000
	Glucose	0.031	0.011	0.146	2.913	0.004
	Age	−0.002	0.001	−0.118	−2.296	0.022
ApoA1/ApoB	Waist circumference	−0.011	0.002	−0.246	−5.086	0.000
	Alcohol consumption	0.087	0.019	0.221	4.512	0.000
	Systolic blood pressure	−0.003	0.001	−0.153	−2.986	0.003
	Age	0.005	0.002	0.166	3.246	0.001
	Glucose	−0.045	0.017	−0.133	−2.692	0.007
Han/female
TC	Glucose	0.223	0.039	0.266	5.645	0.000
TG	Waist circumference	0.024	0.004	0.320	6.964	0.000
TG	Glucose	0.094	0.032	0.135	2.936	0.004
HDL-C	Body mass index	−0.034	0.006	−0.253	−5.330	0.000
LDL-C	Glucose	0.057	0.021	0.131	2.684	0.008
LDL-C	Age	0.005	0.002	0.156	3.209	0.001
ApoA1	Body mass index	−0.009	0.003	−0.153	−3.170	0.002
ApoB	Height	0.006	0.001	0.215	4.562	0.000
	Age	0.003	0.001	0.166	3.349	0.001
	Height	−0.005	0.002	−0.129	−2.580	0.010
ApoA1/ApoB	Age	−0.003	0.001	−0.113	−2.330	0.020
	Glucose	−0.052	0.016	−0.147	−3.208	0.001
	Body mass index	0.193	0.049	1.846	3.928	0.000
	Height	0.074	0.015	1.311	4.827	0.000
	Weight	−0.095	0.021	−2.293	−4.464	0.000
Jing/male
TC	Alcohol consumption	0.313	0.072	0.212	4.356	0.000
	Glucose	0.073	0.023	0.156	3.185	0.002
	Cigarette smoking	0.154	0.050	0.159	3.097	0.002
	Age	0.017	0.003	0.292	5.273	0.000
	Genotype	0.315	0.087	0.172	3.634	0.000
	Pulse pressure	−0.011	0.003	−0.232	−4.453	0.000
	Body mass index	0.097	0.026	0.368	3.800	0.000
	Waist circumference	−0.024	0.008	−0.284	−2.857	0.005
TG	Waist circumference	0.040	0.005	0.426	8.633	0.000
	Cigarette smoking	0.214	0.052	0.198	4.119	0.000
	Height	−0.025	0.007	−0.179	−3.484	0.001
	Age	−0.011	0.003	−0.168	−3.249	0.001
	Glucose	0.066	0.025	0.125	2.666	0.008
HDL-C	Waist circumference	−0.019	0.002	−0.402	−8.995	0.000
HDL-C	Alcohol consumption	0.259	0.037	0.310	6.939	0.000
LDL-C	Cigarette smoking	0.061	0.022	0.139	2.778	0.006
	Genotype	0.091	0.042	0.109	2.161	0.031
	Body mass index	0.012	0.006	0.101	2.001	0.046
ApoA1	Waist circumference	−0.008	0.001	−0.357	−7.594	0.000
ApoA1	Alcohol consumption	0.072	0.018	0.191	4.056	0.000
ApoB	Weight	0.007	0.001	0.314	6.223	0.000
ApoB	Age	0.002	0.001	0.112	2.228	0.026
ApoA1/ ApoB	Waist circumference	−0.015	0.002	−0.375	−7.981	0.000
ApoA1/ ApoB	Alcohol consumption	0.109	0.034	0.150	3.184	0.002
Jing/female
TC	Glucose	0.163	0.031	0.251	5.250	0.000
	Age	0.021	0.004	0.266	5.145	0.000
	Pulse pressure	−0.006	0.003	−0.106	−2.046	0.041
TG	Waist circumference	0.026	0.004	0.291	6.007	0.000
	Cigarette smoking	1.164	0.318	0.174	3.661	0.000
	Height	−0.027	0.006	−0.207	−4.240	0.000
HDL-C	Waist circumference	−0.018	0.003	−0.347	−7.170	0.000
	Genotype	−0.131	0.045	−0.138	−2.920	0.004
	Diastolic blood pressure	0.004	0.002	0.099	2.041	0.042
LDL-C	Genotype	0.123	0.050	0.119	2.463	0.014
	Age	0.008	0.002	0.210	4.293	0.000
	Glucose	0.045	0.016	0.139	2.855	0.005
ApoA1	Body mass index	−0.011	0.004	−0.159	−3.194	0.002
ApoB	Age	0.004	0.001	0.191	3.893	0.000
ApoB	Body mass index	0.010	0.004	0.138	2.805	0.005
ApoA1/ApoB	Body mass index	−0.023	0.005	−0.205	−4.176	0.000
ApoA1/ApoB	Age	−0.004	0.001	−0.144	−2.943	0.003

TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ApoA1 apolipoprotein A1, ApoB apolipoprotein B, ApoA1/ApoB the ratio of apolipoprotein A1 to apolipoprotein B

Back to article page

ISSN: 1476-511X

Contact us

General enquiries: journalsubmissions@springernature.com