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Table 1 Baseline Characteristics Stratefied by Hcy quartiles

From: Relationship between plasma homocysteine level and lipid profiles in a community-based Chinese population

Hcy (μmol/L)

Total

Q1

Q2

Q3

Q4

P-value

P for trend

Median (Min-Max)

11.98 (4.66–141.47)

8.83 (4.66–9.99)

11.02 (10.00–11.97)

13.23 (11.98–14.92)

18.50 (14.93–141.47)

N

4660

1161

1169

1161

1169

  

Age (year-old), mean ± SD

56.75 ± 8.91

53.31 ± 7.41

56.28 ± 7.97

58.59 ± 9.21

58.82 ± 9.72

<0.001

<0.001

Sex, N (%)

 Male

1778 (38.15%)

117 (10.08%)

319 (27.29%)

533 (45.91%)

809 (69.20%)

<0.001

<0.001

 Female

2882 (61.85%)

1044 (89.92%)

850 (72.71%)

628 (54.09%)

360 (30.80%)

  

Scr (μmol/L), mean ± SD

59.44 ± 14.23

57.22 ± 9.05

63.25 ± 11.66

69.08 ± 13.44

77.34 ± 17.78

<0.001

<0.001

TC (mmol/L), mean ± SD

5.34 ± 0.98

5.37 ± 0.99

5.40 ± 0.91

5.35 ± 0.97

5.23 ± 1.03

<0.001

<0.001

TG (mmol/L), Median (IQR)

1.28 (0.91–1.85)

1.24 (0.88–1.84)

1.25 (0.90–1.73)

1.28 (0.94–1.81)

1.35 (0.95–2.01)

<0.001

<0.001

HDL-C (mmol/L), mean ± SD

1.43 ± 0.38

1.49 ± 0.36

1.47 ± 0.36

1.43 ± 0.38

1.36 ± 0.39

<0.001

<0.001

LDL-C (mmol/L), mean ± SD

3.27 ± 0.81

3.28 ± 0.81

3.32 ± 0.77

3.30 ± 0.81

3.19 ± 0.85

<0.001

0.011

FBG (mmol/L), mean ± SD

6.16 ± 1.80

6.12 ± 1.80

6.20 ± 1.91

6.20 ± 1.85

6.10 ± 1.62

0.389

0.728

BMI (Kg/m2), mean ± SD

26.00 ± 3.37

25.86 ± 3.54

25.92 ± 3.31

26.07 ± 3.36

26.1 ± 3.28

0.130

0.019

SBP (mmHg), mean ± SD

133.89 ± 16.85

130.91 ± 16.34

132.90 ± 16.49

135.07 ± 16.91

136.65 ± 17.12

<0.001

<0.001

DBP (mmHg), mean ± SD

75.21 ± 9.95

74.48 ± 9.48

75.07 ± 9.85

74.85 ± 9.86

76.42 ± 10.47

<0.001

<0.001

Pulse (bpm), mean ± SD

78.51 ± 11.41

78.15 ± 10.36

78.25 ± 11.20

78.50 ± 11.61

79.13 ± 12.35

0.159

0.033

Education level, N (%)

 Elementary above

4581 (98.30%)

1150 (99.05%)

1153 (98.63%)

1137 (97.93%)

1141 (97.60%)

0.029

0.003

 Illiterate

79 (1.70%)

11 (0.95%)

16 (1.37%)

24 (2.07%)

28 (2.40%)

Smoking status, N (%)

 Current and former

1249 (26.80%)

96 (8.27%)

230 (19.67%)

356 (30.66%)

567 (48.50%)

<0.001

<0.001

 Never

3411 (73.20%)

1065 (91.73%)

939 (80.33%)

805 (69.34%)

602 (51.50%)

Alcohol drinking, N (%)

 Current and former

1204 (25.84%)

136 (11.71%)

242 (20.70%)

319 (27.48%)

507 (43.37%)

<0.001

<0.001

 Never

3456 (74.16%)

1025 (88.29%)

927 (79.30%)

842 (72.52%)

662 (56.63%)

Physical activity, N (%)

 Once a week above

3737 (80.43%)

896 (77.24%)

928 (79.66%)

971 (83.85%)

942 (80.79%)

<0.001

0.005

 Others

912 (19.57%)

264 (22.76%)

237 (20.34%)

187 (16.15%)

224 (19.21%)

Vitamin B supplement, N (%)

 Once a week above

386 (8.28%)

137 (11.80%)

105 (9.01%)

77 (6.64%)

67 (5.74%)

<0.001

<0.001

 Others

4269 (91.72%)

1024 (88.20%)

1061 (90.99%)

1083 (93.36%)

1101 (94.26%)

  1. Abbreviations: TC Total cholesterol, TG Triglycerides, HDL-C High density lipoprotein cholesterol, LDL-C Low density lipoprotein cholesterol, Hcy Homocysteine, Scr Serum creatinine, BMI Body mass index, FBG Fasting blood glucose, SBP Systolic blood pressure, DBP Diastolic blood pressure, IQR Interquartile range
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Lipids in Health and Disease

ISSN: 1476-511X