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Table 1 Baseline Characteristics Stratefied by Hcy quartiles

From: Relationship between plasma homocysteine level and lipid profiles in a community-based Chinese population

Hcy (μmol/L) Total Q1 Q2 Q3 Q4 P-value P for trend
Median (Min-Max) 11.98 (4.66–141.47) 8.83 (4.66–9.99) 11.02 (10.00–11.97) 13.23 (11.98–14.92) 18.50 (14.93–141.47)
N 4660 1161 1169 1161 1169   
Age (year-old), mean ± SD 56.75 ± 8.91 53.31 ± 7.41 56.28 ± 7.97 58.59 ± 9.21 58.82 ± 9.72 <0.001 <0.001
Sex, N (%)
 Male 1778 (38.15%) 117 (10.08%) 319 (27.29%) 533 (45.91%) 809 (69.20%) <0.001 <0.001
 Female 2882 (61.85%) 1044 (89.92%) 850 (72.71%) 628 (54.09%) 360 (30.80%)   
Scr (μmol/L), mean ± SD 59.44 ± 14.23 57.22 ± 9.05 63.25 ± 11.66 69.08 ± 13.44 77.34 ± 17.78 <0.001 <0.001
TC (mmol/L), mean ± SD 5.34 ± 0.98 5.37 ± 0.99 5.40 ± 0.91 5.35 ± 0.97 5.23 ± 1.03 <0.001 <0.001
TG (mmol/L), Median (IQR) 1.28 (0.91–1.85) 1.24 (0.88–1.84) 1.25 (0.90–1.73) 1.28 (0.94–1.81) 1.35 (0.95–2.01) <0.001 <0.001
HDL-C (mmol/L), mean ± SD 1.43 ± 0.38 1.49 ± 0.36 1.47 ± 0.36 1.43 ± 0.38 1.36 ± 0.39 <0.001 <0.001
LDL-C (mmol/L), mean ± SD 3.27 ± 0.81 3.28 ± 0.81 3.32 ± 0.77 3.30 ± 0.81 3.19 ± 0.85 <0.001 0.011
FBG (mmol/L), mean ± SD 6.16 ± 1.80 6.12 ± 1.80 6.20 ± 1.91 6.20 ± 1.85 6.10 ± 1.62 0.389 0.728
BMI (Kg/m2), mean ± SD 26.00 ± 3.37 25.86 ± 3.54 25.92 ± 3.31 26.07 ± 3.36 26.1 ± 3.28 0.130 0.019
SBP (mmHg), mean ± SD 133.89 ± 16.85 130.91 ± 16.34 132.90 ± 16.49 135.07 ± 16.91 136.65 ± 17.12 <0.001 <0.001
DBP (mmHg), mean ± SD 75.21 ± 9.95 74.48 ± 9.48 75.07 ± 9.85 74.85 ± 9.86 76.42 ± 10.47 <0.001 <0.001
Pulse (bpm), mean ± SD 78.51 ± 11.41 78.15 ± 10.36 78.25 ± 11.20 78.50 ± 11.61 79.13 ± 12.35 0.159 0.033
Education level, N (%)
 Elementary above 4581 (98.30%) 1150 (99.05%) 1153 (98.63%) 1137 (97.93%) 1141 (97.60%) 0.029 0.003
 Illiterate 79 (1.70%) 11 (0.95%) 16 (1.37%) 24 (2.07%) 28 (2.40%)
Smoking status, N (%)
 Current and former 1249 (26.80%) 96 (8.27%) 230 (19.67%) 356 (30.66%) 567 (48.50%) <0.001 <0.001
 Never 3411 (73.20%) 1065 (91.73%) 939 (80.33%) 805 (69.34%) 602 (51.50%)
Alcohol drinking, N (%)
 Current and former 1204 (25.84%) 136 (11.71%) 242 (20.70%) 319 (27.48%) 507 (43.37%) <0.001 <0.001
 Never 3456 (74.16%) 1025 (88.29%) 927 (79.30%) 842 (72.52%) 662 (56.63%)
Physical activity, N (%)
 Once a week above 3737 (80.43%) 896 (77.24%) 928 (79.66%) 971 (83.85%) 942 (80.79%) <0.001 0.005
 Others 912 (19.57%) 264 (22.76%) 237 (20.34%) 187 (16.15%) 224 (19.21%)
Vitamin B supplement, N (%)
 Once a week above 386 (8.28%) 137 (11.80%) 105 (9.01%) 77 (6.64%) 67 (5.74%) <0.001 <0.001
 Others 4269 (91.72%) 1024 (88.20%) 1061 (90.99%) 1083 (93.36%) 1101 (94.26%)
  1. Abbreviations: TC Total cholesterol, TG Triglycerides, HDL-C High density lipoprotein cholesterol, LDL-C Low density lipoprotein cholesterol, Hcy Homocysteine, Scr Serum creatinine, BMI Body mass index, FBG Fasting blood glucose, SBP Systolic blood pressure, DBP Diastolic blood pressure, IQR Interquartile range