Lipids in Health and Disease

Table 2 Multivariate linear regression for effects of Hcy on lipid profiles

From: Relationship between plasma homocysteine level and lipid profiles in a community-based Chinese population

	Model 1		Model 2		Model 3
	β (SE)	P	β (SE)	P	β (SE)	P
LnTG (mmol/L)
LnHcy	0.102 (0.020)	<0.001	0.077 (0.022)	<0.001	0.075 (0.021)	0.001
Hcy < 15 μmol/L	Ref.	-	Ref.	-	Ref.	-
Hcy ≥ 15 μmol/L	0.084 (0.018)	<0.001	0.061 (0.020)	0.001	0.056 (0.020)	0.004
LnHDL-C (mmol/L)
LnHcy	−0.098 (0.010)	<0.001	−0.024 (0.010)	0.021	−0.016 (0.010)	0.115
Hcy < 15 μmol/L	Ref.	-	Ref.	-	Ref.	-
Hcy ≥ 15 μmol/L	−0.082 (0.009)	<0.001	−0.026 (0.010)	0.003	−0.018 (0.009)	0.038
LnTC (mmol/L)
LnHcy	−0.033 (0.007)	<0.001	−0.002 (0.008)	0.739	−0.002 (0.008)	0.771
Hcy < 15 μmol/L	Ref.	-	Ref.	-	Ref.	-
Hcy ≥ 15 μmol/L	−0.029 (0.006)	<0.001	−0.005 (0.006)	0.486	−0.006 (0.007)	0.691
LnLDL-C (mmol/L)
LnHcy	−0.044 (0.010)	<0.001	−0.016 (0.011)	0.095	−0.018 (0.012)	0.133
Hcy < 15 μmol/L	Ref.	-	Ref.	-	Ref.	-
Hcy ≥ 15 μmol/L	−0.039 (0.009)	<0.001	−0.017 (0.009)	0.080	−0.017 (0.010)	0.071

Model 1 univariate analysis
Model 2 adjusted for age and sex
Model 3 adjusted for age, sex, education level, physical activity, vitamin B supplement, body mass index, pulse, fasting glucose, smoking status, drinking status, systolic blood pressure, diastolic blood pressure, serum creatinine
Abbreviations: TC Total cholesterol, TG Triglycerides, HDL-C High density lipoprotein cholesterol, LDL-C Low density lipoprotein cholesterol, Hcy Homocysteine

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