Fig. 1

Effect of taurine on CYP7A1 protein expression in HepG2 cells. a and b, HepG2 cells were treated with taurine (1, 10, 20 mM) for 24 h (n = 6), showed that CYP7A1 protein levels significantly increased in a dose-dependent way after 24 h taurine treatment. c and d, HepG2 cells were treated in 20 mM taurine for 12 h, 24 h and 48 h (n = 3), showed CYP7A1 expression improved and reached a peak at 24 h, and the level of 48 h still significantly increased compared with that of control and 12 h. *P < 0.05 compared with control or corresponding group