Presence of -α3.7Kb -thalassemia (N = 14) | Absence of -α3.7Kb -thalassemia (N = 85) | P1 | |
---|---|---|---|
Median (25th -75th) | Median (25th -75th) | p-value | |
Hemolysis | |||
RBC, x1012/L | 2.9 (2.5–3.3) | 2.5 (2.2–2.7) | 0.012 |
Hemoglobin, g/dL | 8.2 (7.3–8.8) | 7.6 (7.1–8.3) | 0.814* |
Hematocrit, % | 23.8 (21.4–25.5) | 21.7 (19.9–24.1) | 0.839* |
MCV, fL | 80.3 (76.3–83.0) | 88.0 (83.6–93.2) | 0.001 |
MCH, fl | 27.7 (25.7–29.0) | 30.8 (28.8–32.7) | 0.001 |
Total bilirubin, mg/dL | 1.8 (1.2–2.7) | 2.8 (1.7–3.9) | 0.026 |
Direct bilirubin, mg/dL | 0.4 (0.2–0.5) | 0.5 (0.3–0.6) | 0.180 |
Indirect bilirubin, mg/dL | 1.3 (0.9–2.2) | 2.3 (1.3–3.4) | 0.026 |
LDH, U/L | 958.0 (852.2–1845.7) | 1120.0 (762.5–1693.0) | 0.848* |
Reticulocyte count | 4.6 (3.7–8.6) | 5.8 (4.3–8.1) | 0.736* |
Hemoglobin profile | |||
Fetal hemoglobin, % | 9.4 (3.4–13.9) | 9.3 (5.2–14.4) | 0.651 |
NO metabolites | |||
NOm, μM | 33.9 (20.7–44.4) | 35.7 (28.8–48.0) | 0.400 |
Leukocytes | |||
WBC, x 109/L | 12.3 (7.6–14.8) | 14.0 (11.2–16.1) | 0.161 |
Neutrophil, x 109/L | 5124.0 (3830.2–7061.7) | 5796.0 (4208.5–7225.0) | 0.550 |
Eosinophil, x 109/L | 582.5 (232.5–1936.5) | 800.0 (303.50–1785.5) | 0.676* |
Lymphocyte, x 109/L | 3711.0 (2695.5–6960.7) | 5688.0 (4533.0–7269.0) | 0.036 |
Monocyte, x 109/L | 202.0 (124.5–432.7) | 380.0 (252.0–702.0) | 0.120* |
Platelets | |||
Platelet, x103/mL | 335.5 (239.2–443.0) | 450.0 (382.0–559.0) | 0.003 |
Lipid profile | |||
Total Cholesterol, mg/dL | 118.5 (106.7–142.2) | 123.0 (97.5–148.0) | 0.810 |
HDL-C, mg/dL | 30.0 (24.7–38.0) | 32.0 (27.0–37.5) | 0.376 |
LDL-C, mg/dL | 68.0 (56.7–99.5) | 67.0 (41.0–87.0) | 0.396 |
VLDL-C, mg/dL | 22.5 (18.0–28.7) | 22.0 (16.5–32.0) | 0.936 |
Triglycerides, mg/dL | 111.0 (89.5–142.5) | 110.0 (82.5–158.5) | 0.928 |