A Single Nucleotide Polymorphism in the FADS1 Gene is Associated with Plasma Fatty Acid and Lipid Profiles and Might Explain Gender Difference in Body Fat Distribution

Table 7 The association between rs174547 and lipid profiles in women (N = 586)

Indices	Effect (SD)	P value^a			Effect (SD)	P value^b			Effect (SD)	P value^c
Indices	Effect (SD)	Addictive	Dominant	Recessive	Effect (SD)	Addictive	Dominant	Recessive	Effect (SD)	Addictive	Dominant	Recessive
TG (mmol/l)	−0.09 (0.09)	0.541	0.888	0.344	−0.02 (0.09)	0.924	0.946	0.796	0.03 (0.08)	0.894	0.714	0.842
TC (mmol/l)	−0.03 (0.05)	0.513	0.607	0.564	−0.03 (0.08)	0.692	0.687	0.811	−0.01 (0.05)	0.822	0.828	0.881
HDL-C (mmol/l)	−0.04 (0.03)	0.155	0.119	0.469	−0.04 (0.06)	0.624	0.526	0.897	−0.02 (0.06)	0.817	0.724	0.996
LDL-C (mmol/l)	−0.04 (0.04)	0.386	0.426	0.531	−0.03 (0.02)	0.067	0.081	0.214	−0.04 (0.02)	0.035*	0.037*	0.183
Apoa1 (g/L)	0.02 (0.03)	0.754	0.891	0.460	0.01 (0.03)	0.989	0.789	0.764	−0.01 (0.03)	0.797	0.600	0.870
Apob (g/L)	−0.03 (0.02)	0.150	0.330	0.145	−0.01 (0.01)	0.320	0.424	0.392	−0.01 (0.02)	0.530	0.686	0.509

^aAdujsted for age; ^bAdjusted for age, income, smoking, drinking, physical activity and BMI; ^cAdjusted for age, income, smoking, drinking, physical activity, BMI, and android fat mass percent; TG triglyceride, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C high low-density lipoprotein cholesterol, Apoa1 Apolipoprotein A1, Apob Apolipoprotein B; *P < 0.05

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