Fig. 3

Expression of eight selected genes showing altered expression in patient groups vs. controls. (a) mRNA expression (2.0-fold change) relative to β-actin mRNA in PBMCs obtained from controls, and hyperlipidaemia and CHD patients post-bypass surgery, as determined by qRT-PCR. Data are presented as the mean 2.0-fold change relative to control ± SEM (n = 10). (b) Plasma levels (pg/ml) of PPBP and α-defensin 1–3 from healthy controls (n = 20), hyperlipidaemia patients (n = 24), and CHD patients post-bypass surgery (n = 21). Data are illustrated as whisker plots, with boxes denoting the interquartiles range (IQR) and whiskers the minimum/maximum values. (c) Correlations between relative expression of PPBP and DEFA1/DEFA3, and between plasma levels of PPBP and α-defensin 1–3. ^*refers to a significant difference (p > 0.05)