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Table 2 Patients’ demographics in SLE and controls

From: Low apolipoprotein M serum levels correlate with Systemic lupus erythematosus disease activity and apolipoprotein M gene polymorphisms with Lupus

Clinical parameter

SLE patients

Healthy Controls

P value

Patients (number)

52

52

Age (years)

31 (12–52)

32 (20–56)

0.438

Female:Male ratio

46:6

45:7

0.767

Laboratory data

 TG (mmol/L)

1.62 (0.50–8.93)

0.80 (0.35–2.52)

<0.001

 TC (mmol/L)

4.18 (1.92–9.28)

4.28 (3.25–5.52)

0.207

 HDL (mmol/L)

1.06 (0.35–2.01)

1.44 (1.05–2.15)

<0.001

 LDL (mmol/L)

2.50 (0.89–7.06)

2.53 (1.44–3.78)

0.062

 APOA1 (g/L)

1.14 (0.57–2.01)

1.45 (1.08–1.89)

<0.001

 APOB (g/L)

0.93 (0.38–2.06)

0.89 (0.57–1.25)

0.002

 APOM (mg/L)

2.92 (1.54-17.75)

14.80 (3.53–56.07)

<0.001

 Lpa (mg/L)

154.15 (9.70–1517.40)

78.80 (3.40–1043.50)

0.041

 hs-CRP (mg/L)

2.26 (0.12–125.44)

0.37 (0.04–5.68)

0.008

 25-OHD3 (ng/ml)

9.72 (3.00-19.26)

16.16 (6.98-34.22)

<0.001

 Anti-dsDNA antibodies (%)

19 (36.5%)

 Anti-SM antibodies (%)

21 (40.4%)

 SLEDAI

15 (5-29)

  1. Data are presented as median (minimum-maximum). P < 0.05 was considered statistically significant
  2. TG triglyceride, TC total cholesterol, HDL-C high-densitylipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, APOA1 apolipoprotein A1, APOB apolipoprotein B, APOM apolipoprotein M, Lpa lipoprotein(a), hs-CRP high-sensitivity C-reactive protein, SLEDAI systemic lupus erythematosus disease activity index