Radiotherapy improves serum fatty acids and lipid profile in breast cancer

Table 1 Free fatty acid profile of BC patients (pre and post) in comparison with controls

Free fatty acids	Controls	Pre-treated BC patients	Post-treated BC patients
C-14: 0	1.26 ± 0.96	1.30 ± 0.30	0.81 ± 0.44
C-15: 0	ND	0.57 ± 0.24	ND
C-16: 0	18.17 ± 5.06	23.0 ± 2.86^*	28.2 ± 2.47^*
C-18: 0	13.89 ± 3.56	21.8 ± 2.00^*	15.9 ± 1.76^¶
C-14: 1	0.75 ± 0.49	1.86 ± 0.51	0.04 ± 0.01
C-16: 1	2.619 ± 1.37	1.85 ± 0.48	2.66 ± 0.96
C-18: 1	19.71 ± 2.276	27.3 ± 1.63^*	26.5 ± 2.01^*
C-18: 2 (n-6)	29.14 ± 3.28	20.2 ± 1.65^*	19.84 ± 2.37*
C-18: 3 (n-3)	1.54 ± 0.79	1.21 ± 0.836^*	0.76 ± 0.40*
C-20: 3 (n-6)	0.65 ± 0.3	0.39 ± 0.19	0.6 ± 0.47
C-20: 4 (n-6)	7.76 ± 2.40	1.09 ± 0.52^*	2.7 ± 1.55^*¶
C-22: 6 (n-3)	1.18 ± 0.79	0.47 ± 0.24	1.88 ± 1.74
C-18:0: C-18:1	0.719 ± 0.24	0.79 ± 0.06	0.605 ± 0.090
C-18:2: C-18:1	1.5 ± 0.28	0.074 ± 0.03	0.75 ± 0.118
C-18:3: C-18:1	0.071 ± 0.033	2.8 ± 0.97^*	0.008 ± 0.002^*¶
n-3: n-6	7.4 ± 1.41	2.80 ± 1.01^*	3.43 ± 1.71*^¶
Sat: unsat FA’s	35.2 ± 6.05	25.0 ± 1.34^*	26.6 ± 3.47^*
D5 Desaturase	21.2 ± 19.1	3.83 ± 3.4^*	7.84 ± 1.2
D6 Desaturase	0.019 ± 0.009	0.03 ± 0.02	0.02 ± 0.013

Values represent mean ± standard deviation of triplicates. The different symbol on the same row indicates the Significant difference at p < 0.05. *p < 0.05 shows the comparison between pre and post treated BC patients with controls, ¶ p < 0.05 shows the comparison between pre-treated BC patients and post treated BC patients. Lauric acid (C12:0), Myristic acid (C14:1), myristoleic acid (C14:1), Pentadecyclic acid (C15:0), palmitic acid (C16:0), palmitoleic acid (C16:1), stearic acid (C18:0), oleic acid (C18:1), linoleic acid (C18:2), α-linolenic acid (C18:3), C20:3 (Dihomo-γ-linolenic acid), arachidonic acid (C20:4) and docosahexaenoic acid (DHA (C22:6). D5 Desaturase was calculated as 20:4n-6/20:3n-6 ratio. D6 Desaturase was calculated as 20:3n-6/18:2n-6 ratio. Sat: unsat FA’s shows saturated and unsaturated fatty acids ratio

ISSN: 1476-511X