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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Intracellular high cholesterol content disorders the clock genes, apoptosis-related genes and fibrinolytic-related genes rhythmic expressions in human plaque-derived vascular smooth muscle cells

Fig. 1

Circadian expressions of Fas, p53, Bax, t-PA and PAI-1 at mRNA levels in NVSMCs and PVSMCs. The mRNA expression levels of Fas (a), p53 (b), Bax (c), t-PA (d) and PAI-1 (e) were determined by qRT-PCR at indicated time points after serum shock, and were normalized to GAPDH mRNA levels. The signal levels at ZT0 of NVSMCs were defined as 1. Each value was presented as mean ± SD (n1 = 9 of NVSMCs samples; n2 = 23 of PVSMCs samples). Unpaired student’s t test was used to assess the expression differences between two groups. *p < 0.05 and**p < 0.01 in PVSMCs versus NVSMCs

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