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Fig. 4 | Lipids in Health and Disease

Fig. 4

From: Intracellular high cholesterol content disorders the clock genes, apoptosis-related genes and fibrinolytic-related genes rhythmic expressions in human plaque-derived vascular smooth muscle cells

Fig. 4

Effects of Ox-LDL on the rhythmic expressions of clock genes and CCGs in the VSMCs. The mRNA levels of Bmal1 (a), CLOCK (b), Per2 (c), Cry1 (d), Rev-erbα (e), t-PA (f), PAI-1 (g), Fas (h), p53 (i) and Bax (j) in VSMCs with or without ox-LDL treatment were determined by qRT-PCR at indicated time points after serum shock. Their expression levels were normalized to GAPDH mRNA levels. The signal levels at ZT0 of NC were defined as 1. Each value was presented as mean ± SD (n = 6 of each group). Unpaired student’s t test was used to assess the expression differences between two groups. *p < 0.05 versus NC

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Lipids in Health and Disease

ISSN: 1476-511X