A new use for an old index: preoperative high-density lipoprotein predicts recurrence in patients with hepatocellular carcinoma after curative resections

Table 3 The correlation between clinicopathologic characteristics and HDL_PO in the validation cohort

		Number (n = 182)	Low-HDL_PO group (n = 35)	High-HDL_PO group (n = 147)	P value
Sex	Male	158	32	126	0.371^a
	Female	24	3	21	0.371^a
Age	≤50	64	13	51	0.845
	>50	118	22	96	0.845
Tumor number	Single	144	27	117	0.817
	Multiple	38	8	30	0.817
Tumor size	≤5	115	19	96	0.246
	>5	67	16	51	0.246
Tumor encapsulation	None	112	19	93	0.340
	Complete	70	16	54	0.340
Satellite lesions	No	160	30	130	0.663^a
	Yes	22	5	17	0.663^a
Vascular invasion	No	112	19	93	0.340
	Yes	70	16	54	0.340
Tumor grade	I-II	114	16	98	0.032
	III-IV	68	19	49	0.032
Child-Pugh grade	A	171	31	140	0.138^a
	B	11	4	7	0.138^a
BCLC stage	0 + A	130	25	105	0.575
	B + C	52	10	42	0.575
AFP,μg/L	≤400	135	22	113	0.131
	>400	47	13	34	0.131
ALT,μg/L	≤40	170	34	136	0.278^a
	>40	12	1	11	0.278^a
GGT,IU/L	≤54	101	19	82	1.000
	>54	81	16	65
HbsAg	Negative	23	1	22	0.053^a
	Positive	159	34	125
Recurrence	No	97	11	86	0.005
	Yes	85	24	61

Abbreviations: AFP, α-fetoprotein; ALT, alanine aminotransferase; GGT, γ-glutamyl transpeptadase; HBsAg, hepatitis B surface antigen; BCLC, Barcelona Clinic Liver Cancer ^aFisher’s exact test

ISSN: 1476-511X