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Table 3 Concentrations of EPA, DPA and DHA in the blood and tissues of Pten-knockout mice1

From: Dietary supplementation of α-linolenic acid induced conversion of n-3 LCPUFAs and reduced prostate cancer growth in a mouse model

   Group4, %
Tissue Fatty acid CON L-ALA H-ALA EPA n-3 n-6
blood EPA ND2,a 4.05 ± 0.31b 7.22 ± 0.28c 10.1 ± 0.75e 8.90 ± 0.37d NDa
  DPA NDa 1.54 ± 0.04c 2.14 ± 0.07d 2.57 ± 0.18e 1.20 ± 0.04b NDa
  DHA 1.69 ± 0.11b 5.50 ± 0.21d 4.49 ± 0.29c 6.19 ± 0.24d 9.90 ± 0.52e 0.78 ± 0.09a
  Total3 1.69 ± 0.11a 11.1 ± 0.46b 13.9 ± 0.54c 19.8 ± 0.53d 20.0 ± 0.83d 0.78 ± 0.09a
liver EPA NDa 4.90 ± 0.39b 9.68 ± 0.46c 8.29 ± 0.83c 5.77 ± 0.52b NDa
  DPA 0.11 ± 0.00a 1.58 ± 0.11b 2.18 ± 0.14c 3.90 ± 0.45d 1.84 ± 0.14b,c 0.12 ± 0.02a
  DHA 1.70 ± 0.17a 10.9 ± 1.24b 9.41 ± 0.59b 14.0 ± 0.57c 22.0 ± 0.77d 1.98 ± 0.21a
  Total 1.72 ± 0.18a 18.8 ± 1.04b 21.3 ± 0.80c 26.2 ± 1.19d 29.6 ± 0.80e 2.07 ± 0.22a
epididymal fat pad EPA NDa 0.11 ± 0.01a 0.20 ± 0.01a 2.31 ± 0.15c 1.49 ± 0.18b NDa
  DPA NDa 0.17 ± 0.01a 0.28 ± 0.01b 0.86 ± 0.09c 0.93 ± 0.07c NDa
  DHA NDa 0.18 ± 0.02a 0.16 ± 0.03a 0.64 ± 0.07b 2.76 ± 0.23c NDa
  Total NDa 0.46 ± 0.03a,b 0.64 ± 0.03b 3.81 ± 0.28c 5.17 ± 0.44d NDa
prostate EPA NDa 2.04 ± 0.26b 3.82 ± 0.41c 4.33 ± 0.96c 3.43 ± 0.54c NDa
  DPA NDa 2.30 ± 0.28b 4.12 ± 0.30c 4.14 ± 0.73c 1.75 ± 0.13b NDa
  DHA 2.18 ± 0.10a 4.80 ± 0.54b 5.14 ± 0.13b 7.58 ± 0.63c 9.93 ± 0.72d 1.01 ± 0.13a
  Total 2.18 ± 0.10a 9.15 ± 0.87b 13.1 ± 0.28c 16.1 ± 2.18d 15.1 ± 0.95c,d 1.01 ± 0.13a
  1. 1Values are means ± SEMs (n = 6). Labeled means without a common letter differ, p < 0.05
  2. 2ND, not detected
  3. 3Total, the sum of EPA, DPA and DHA
  4. 4Data expressed as percentage of total fatty acids. L-ALA, low-ALA; H-ALA, high-ALA; CON, control