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Table 1 The demographic, clinical and biochemical characteristics of controls and patients

From: Association of plasma fatty acid alteration with the severity of coronary artery disease lesions in Tunisian patients

Variables

Controls (n = 120)

Non-CAD group (n = 39)

CAD group (n = 111)

Sexe n (%)

 Male

53 (44)

16 (41)

80 (72)**

 Femelle

67 (56)

23 (59)**

31 (28)**

Age (years)

57.10 ± 12.65

60.20 ± 9

60.83 ± 9

Current smoking n (%)

14 (12)

7 (18)

38 (34)**

Diabetes n (%)

0 (0)

15 (38)**

43 (39)**

Hight blood pressure n (%)

0 (0)

25 (64)**

52 (47)**

Hyperlipidemia n (%)

0 (0)

15 (38)**

50 (45)**

BMI (kg/m2)

27.73 ± 3.43

30.23 ± 4.65*

29.44 ± 4.28*

Obesity n (%)

0 (0)

22 (56)**

46 (41)**

Menopause n (%)

26 (22)

20 (51)**

28 (25)

family history n (%)

0 (0)

10 (26)**

24 (22)**

Medications n (%)

 Statins

0 (0)

16 (41)**

35 (31)**

 antiagreguant

0 (0)

20 (51)**

66 (59)**

 ACE-I

0 (0)

21 (54)**

65 (59)**

 BETA-Bloker

0 (0)

20 (51)**

56 (50)**

 Hypoglycemic drug

0 (0)

7 (18)**

31 (30)**

 Fibrate

0 (0)

8 (20)**

36 (32)**

Gensini score

 

0 (0, 3)

28 (13, 52)

Total cholesterol (mmol/L)

4.80 ± 0.78

4.95 ± 0.86

4.97 ± 0.99

LDL-C (mmol/L)

3.1 ± 0.81

3.13 ± 0.85

3.11 ± 0.92

HDL-C (mmol/L)

1.22 ± 0.44

1 ± 0.22*

1.01 ± 0.24**

Triglycerides (mmol/L)

1.33 ± 0.38

1.8 ± 1.03*

1.83 ± 0.86**

Creatinine (μmol/L)

85.14 ± 14.06

84.81 ± 22.68

100.16 ± 23.45**

Urea (μmol/L)

5.31 ± 1.68

5.9 ± 2.21

6.62 ± 3**

hs-CRP (mg/L)

1.22 ± 0.95

2.33 ± 1.5**

3.03 ± 2.26**

Glucose (mmol/ L)

5.1 ± 0.8

8.14 ± 5.43**

9.62 ± 4.7**

Hemoglobin A1c (%)

5.24 ± 0.92

7.46 ± 3.01**

8.61 ± 3.06**

ApoA1 (g/l)

1.30 ± 0.15

1.13 ± 0.16**

1.12 ± 0.17**

APoB (g/l)

0.6 ± 0.14

0.75 ± 0.14**

0.77 ± 0.24**

Total cholesterol /HDL

4.31 ± 1.45

5.21 ± 1.61*

5.19 ± 1.76**

Triglycerides /HDL

1.23 ± 0.57

2.04 ± 1.85*

1.96 ± 1.09**

LDL/HDL

2.87 ± 1.30

3.27 ± 1.18*

3.3 ± 1.48*

ApoB/ApoA1

0.47 ± 0.13

0.68 ± 0.19**

0.7 ± 0.21**

  1. Data are expressed as n (%) (number of persons, (percent)), mean ± SD (standard deviation) or median (interquartile, range). A significant difference between controls and coronary artery disease patients is indicated by * (Mann Whitney Test). *: p < 0.05. A significant difference between controls and patients (Non-CAD group and CAD group) is indicated by * (p < 0.05) or ** (p < 0.001). ApoA1: Apolipoprotein A1; ApoB: Apolipoprotein B; CAD: coronary artery disease; BMI: body mass index; LDL-C: low-density lipoprotein-cholesterol; HDL-C: high-density lipoprotein-cholesterol; hs-CRP: high sensitive-C reactive protein; ACE-I: angiotensin-converting enzyme inhibitor
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Lipids in Health and Disease

ISSN: 1476-511X