Table 3 Univariate and multivariate Cox Proportional Hazard models of development of HTN during 9-year follow-up
Variables | Univariate models | Multivariate models | ||
|---|---|---|---|---|
HR (95%CI) | P value | HR (95%CI) | p value | |
Gender (male) | 1.62 (1.46–1.78) | < 0.001 | 1.33 (1.14–1.56) | < 0.001 |
Age (years) | 1.03 (1.03–1.04) | < 0.001 | 1.03 (1.02–1.03) | < 0.001 |
BMI (kg/m2) | 1.16 (1.15–1.18) | < 0.001 | 1.09 (1.06–1.12) | < 0.001 |
WC (cm) | 1.06 (1.05–1.06) | < 0.001 | 1.01 (1.00–1.02) | 0.017 |
BUN (mmol/L) | 1.11 (1.07–1.15) | < 0.001 | 1.00 (0.96–1.04) | 0.967 |
Cr (μmol/L) | 1.00 (1.00–1.01) | < 0.001 | 1.00 (1.00–1.01) | 0.018 |
FPG (mmol/L) | 1.26 (1.21–1.30) | < 0.001 | 1.10 (1.03–1.18) | 0.006 |
UA (μmol/L) | 1.01 (1.00–1.00) | < 0.001 | 1.00 (1.00–1.00) | 0.006 |
AST (U/L) | 1.01 (1.00–1.01) | < 0.001 | 1.00 (1.00–1.01) | 0.648 |
ALT (U/L) | 1.00 (1.00–1.00) | < 0.001 | 1.00 (1.00–1.00) | 0.433 |
γ-GGT (U/L) | 1.00 (1.00–1.01) | < 0.001 | 1.00 (1.00–1.00) | 0.001 |
TC (mmol/L) | 1.28 (1.22–1.34) | < 0.001 | 1.16 (0.95–1.43) | 0.144 |
TG (mmol/L) | 1.29 (1.25–1.33) | < 0.001 | 1.08 (0.94–1.24) | 0.264 |
HDL-C (mmol/L) | 0.86 (0.77–0.97) | 0.010 | 0.96 (0.74–1.25) | 0.756 |
LDL-C (mmol/L) | 1.31 (1.24–1.38) | < 0.001 | 0.84 (0.70–1.02) | 0.073 |
Apo-A1 (g/L) | 1.02 (0.86–1.21) | 0.812 | 1.07 (0.86–1.33) | 0.562 |
Apo-B (g/L) | 3.47 (2.95–4.09) | < 0.001 | 1.15 (0.78–1.70) | 0.490 |
eGFR (mL/(min·1.73 m2)) | 1.00 (0.99–1.00) | < 0.001 | 1.00 (1.00–1.00) | 0.238 |
TyG | < 0.001 | 0.013 | ||
Quartile 1 | 1.00 (reference) | 1.00 (reference) | ||
Quartile 2 | 1.38 (1.20–1.59) | 1.21 (1.00–1.47) | ||
Quartile 3 | 2.00 (1.74–2.29) | 1.49 (1.16–1.93) | ||
Quartile 4 | 2.63 (2.31–3.00) | 1.53 (1.07–2.19) | ||